Description

2-Thiophenecarbonyl Chloride, 4-Chloro- (9Ci) is a specialized heterocyclic acid chloride derivative, serving as a critical building block in advanced organic synthesis. Its value lies in its high reactivity, enabling the efficient introduction of the 4-chlorothiophene-2-carbonyl moiety into target molecules. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs) with thiophene-based scaffolds, potentially for antiviral, anti-inflammatory, or CNS-targeting drugs.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides, where the chlorinated thiophene structure can confer specific biological activity.
• Material Science Research: Acts as a monomer or functionalization agent in the creation of specialty polymers, liquid crystals, or organic electronic materials.
• Chemical Biology & Proteomics: Employed as a coupling reagent or labeling agent for modifying peptides, proteins, or other biomolecules in research settings.
• Dye & Pigment Manufacturing: Serves as an intermediate for synthesizing complex heterocyclic dyes and organic pigments.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom chemical synthesis services catering to R&D and pilot-scale production.

Basic Information

Product Name	2-Thiophenecarbonyl Chloride, 4-Chloro- (9Ci)
CAS No.	66039-95-0
Molecular Formula	C5H2Cl2OS
Molecular Weight	180.04 g/mol
Synonyms	4-Chlorothiophene-2-carbonyl chloride; 4-Chloro-2-thiophenecarbonyl chloride; 4-Chloro-2-thenoyl chloride; 4-Chlorothiophene-2-carboxylic acid chloride; 2-Thenoyl chloride, 4-chloro-; 4-Chloro-2-thienoyl chloride; 66039-95-0; 4-Chlorothiophene-2-carboxyl chloride
EINECS	Contact for details

Quality Control

Our 2-Thiophenecarbonyl Chloride, 4-Chloro- (9Ci) is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistent performance. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and reacts with water; ensure containers are kept tightly sealed under an inert atmosphere if necessary. Keep away from strong bases, alcohols, and oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.