Description

Vagistat CAS NO 65899-73-2 is a high-purity active pharmaceutical ingredient (API) known for its potent antifungal properties. This compound is critical for ensuring the efficacy and safety of pharmaceutical formulations targeting specific fungal infections. It is primarily required by manufacturers in the pharmaceutical and biotechnology sectors for the development and production of topical and vaginal antifungal medications.

Application

• Pharmaceutical API: Core active ingredient in the formulation of prescription and over-the-counter (OTC) antifungal creams, ointments, and suppositories.
• Topical Antifungal Treatments: Used in medicated products designed for the treatment of cutaneous candidiasis and other dermatological fungal infections.
• Vaginal Antifungal Preparations: Essential component in intravaginal products for the treatment of vulvovaginal candidiasis (yeast infections).
• Veterinary Pharmaceuticals: Incorporated into antifungal treatments for veterinary use, addressing similar fungal conditions in animals.
• Research & Development: Serves as a reference standard and key intermediate in pharmaceutical R&D for novel antifungal agents.

Basic Information

Product Name	Vagistat
CAS No.	65899-73-2
Molecular Formula	C18H15I3N2O4
Molecular Weight	720.04 g/mol
Synonyms	Tioconazole; Trosyd; 1-[2-[(2-Chloro-3-thienyl)methoxy]-2-(2,4-dichlorophenyl)ethyl]-1H-imidazole; Vagistat-1; Gyno-Trosyd; Tioctan; UK-20349; Antifungal Agent UK-20349
EINECS	266-104-6

Quality Control

Our Vagistat (Tioconazole) is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure it meets stringent pharmacopeial standards, including identification, purity, and impurity profile assessments. A Certificate of Analysis (COA) detailing results for Assay, Related Substances, Residual Solvents, and Heavy Metals is provided with every shipment to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Due to its hygroscopic nature, protect from moisture. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to almost white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Water Content (KF)	NMT 1.0%
Related Substances (HPLC)	Total impurities: NMT 2.0% Any individual impurity: NMT 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Heavy Metals	NMT 20 ppm
Sulfated Ash	NMT 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.