Description

2,2,2-Trifluoro-1-Phenylethyl Azide is a specialized organic azide building block characterized by its trifluoromethyl and phenyl substituents. This compound is highly valued for its role as a versatile precursor in click chemistry, particularly in the synthesis of 1,2,3-triazoles via copper-catalyzed azide-alkyne cycloaddition (CuAAC). It is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and materials science industries who require high-purity intermediates for drug discovery, chemical biology, and the development of advanced polymers.

Application

• Pharmaceutical Intermediate: A key precursor for synthesizing trifluoromethylated triazole derivatives with potential biological activity.
• Click Chemistry Reagent: Used in CuAAC reactions for the efficient, modular construction of complex molecules in drug discovery and chemical biology.
• Agrochemical Synthesis: Serves as a building block for developing novel crop protection agents containing the trifluoromethyl group.
• Materials Science: Employed in the synthesis of functionalized polymers and advanced materials with tailored properties.
• Bioconjugation: Facilitates the labeling and modification of biomolecules for diagnostic and research applications.
• Academic & Industrial R&D: A valuable tool for synthetic organic chemists exploring new reaction methodologies and compound libraries.

Basic Information

Product Name	2,2,2-Trifluoro-1-Phenylethyl Azide
CAS No.	65874-91-1
Molecular Formula	C8H6F3N3
Molecular Weight	201.15 g/mol
Synonyms	α-Azido-2,2,2-trifluoroethylbenzene; 1-Azido-2,2,2-trifluoro-1-phenylethane; 2,2,2-Trifluoro-1-azidoethylbenzene; (Azido)(phenyl)trifluoroethane; Phenylethyl Azide, 2,2,2-Trifluoro-; Trifluoromethylphenyl Azide
EINECS	Contact for details

Quality Control

Our 2,2,2-Trifluoro-1-Phenylethyl Azide is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and FTIR, to ensure high purity and structural identity. A detailed Certificate of Analysis (COA) documenting purity, assay, and impurity profiles is provided with every shipment to guarantee reproducibility and reliability for your critical R&D and production processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, well-ventilated place at temperatures between 2°C and 8°C (refrigerated) to minimize decomposition and mitigate risks associated with its highly volatile and easily oxidized nature. For long-term storage, consider maintaining the material under an inert atmosphere such as nitrogen or argon.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.