Description

3-Pyrrolidinecarbonylchloride,2,2,5,5-Tetramethyl-(9Ci) is a high-purity, specialized organic building block of significant interest in advanced synthetic chemistry. Its value lies in its rigid, sterically hindered pyrrolidine structure, which serves as a key intermediate for constructing complex molecules with precise stereochemistry. This compound is primarily sought by researchers and process chemists in the pharmaceutical and agrochemical industries for the development of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A critical building block for synthesizing novel drug candidates, particularly in medicinal chemistry programs targeting central nervous system (CNS) disorders and other therapeutic areas.
• Agrochemical Synthesis: Used in the research and development of advanced pesticides and herbicides, where its unique structure can contribute to improved efficacy and selectivity.
• Ligand and Catalyst Development: Serves as a precursor for creating chiral ligands and organocatalysts used in asymmetric synthesis to produce enantiomerically pure compounds.
• Material Science Research: Employed in the synthesis of specialty polymers and advanced organic materials with tailored properties.
• Chemical Biology Probes: Useful for constructing molecular probes and inhibitors to study biological pathways and enzyme functions.

Basic Information

Item	Detail
Product Name	3-Pyrrolidinecarbonylchloride,2,2,5,5-Tetramethyl-(9Ci)
CAS No.	65870-61-3
Molecular Formula	C9H16ClNO
Molecular Weight	189.68 g/mol
Synonyms	2,2,5,5-Tetramethyl-3-pyrrolidinecarbonyl chloride; 1-(Chlorocarbonyl)-2,2,5,5-tetramethylpyrrolidine; 2,2,5,5-Tetramethylpyrrolidine-3-carbonyl chloride; Tetramethylproline acid chloride; 3-Carbamoyl-2,2,5,5-tetramethylpyrrolidine hydrochloride (related); Proline derivative, 2,2,5,5-tetramethyl-, acid chloride
EINECS	Contact for details

Quality Control

Our 3-Pyrrolidinecarbonylchloride,2,2,5,5-Tetramethyl-(9Ci) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure high chemical purity and identity confirmation. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all relevant specifications. Our quality commitment ensures material consistency and reliability for your critical research and development processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline solid or powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.