Description

2-Furancarbonyl Chloride, 5-(Trifluoromethyl)- (9Ci) is a specialized heterocyclic building block featuring a reactive acid chloride group and a trifluoromethyl substituent. This compound is highly valued for its ability to introduce the 5-(trifluoromethyl)furan-2-carbonyl moiety into target molecules, a key structural motif in advanced material and pharmaceutical research. It is primarily sought by R&D chemists and process development scientists in the agrochemical, pharmaceutical, and material science industries for synthesizing novel active ingredients and functional polymers.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel drug candidates, particularly in medicinal chemistry programs targeting bioactive molecules with furan and trifluoromethyl groups.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the trifluoromethyl group can enhance biological activity and environmental stability.
• Material Science Precursor: Serves as a monomer or cross-linking agent in the synthesis of specialty polymers, coatings, and liquid crystals with tailored properties.
• Organic Synthesis Building Block: Employed in academic and industrial laboratories for constructing complex heterocyclic compounds via amidation, esterification, and other nucleophilic acyl substitution reactions.
• Fluorine Chemistry Research: A valuable reagent for studying the influence of the trifluoromethyl group on the reactivity and electronic properties of furan-based systems.

Basic Information

Product Name	2-Furancarbonyl Chloride, 5-(Trifluoromethyl)- (9Ci)
CAS No.	65865-25-0
Molecular Formula	C6H2ClF3O2
Molecular Weight	198.53 g/mol
Synonyms	5-(Trifluoromethyl)furan-2-carbonyl chloride; 5-(Trifluoromethyl)-2-furoyl chloride; 2-Furoyl chloride, 5-(trifluoromethyl)-; α-Trifluoromethyl-2-furoyl chloride; 5-Trifluoromethyl-2-furancarboxylic acid chloride; 5-Trifluoromethyl-2-furoyl chloride; 5-Trifluoromethylfuran-2-carbonyl chloride
EINECS	Contact for details

Quality Control

Our 2-Furancarbonyl Chloride, 5-(Trifluoromethyl)- (9Ci) is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure high purity and consistent performance. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available upon request to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic and moisture-sensitive nature, the container should be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) to prevent decomposition. Recommended storage temperature is 2-8°C for long-term stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.