Description

N(4) Anisoyl-2'-Deoxycytidine 5'-Monophosphate Pyridinium is a chemically modified nucleotide derivative, specifically a protected form of deoxycytidine monophosphate. This compound is of significant value in oligonucleotide synthesis and pharmaceutical research, where it serves as a crucial building block for creating modified DNA sequences. It is primarily needed by biotechnology companies, academic research institutions, and pharmaceutical developers working on antisense oligonucleotides, diagnostic probes, and therapeutic nucleic acids.

Application

• Oligonucleotide Synthesis: A key phosphoramidite precursor for the solid-phase synthesis of modified DNA strands, particularly useful in introducing site-specific modifications.
• Antisense Therapy Development: Used in the research and production of antisense oligonucleotides (ASOs) designed to target specific RNA sequences for therapeutic purposes.
• Diagnostic Probe Manufacture: Essential for creating labeled probes used in techniques like FISH (Fluorescence In Situ Hybridization) and PCR for genetic testing and molecular diagnostics.
• Pharmaceutical Intermediates: Acts as a critical intermediate in the synthesis of nucleotide-based active pharmaceutical ingredients (APIs) and prodrugs.
• Biochemical Research: Employed in academic and industrial labs to study DNA-protein interactions, enzyme mechanisms, and nucleic acid chemistry.
• CRISPR/Cas9 & Gene Editing: Used in the synthesis of guide RNAs or donor DNA templates where specific, high-purity nucleotide modifications are required.

Basic Information

Item	Details
Product Name	N(4) Anisoyl-2'-Deoxycytidine 5'-Monophosphate Pyridinium
CAS No.	65762-47-2
Molecular Formula	C21H24N3O9P
Molecular Weight	493.41 g/mol
Synonyms	5'-O-Monophosphate, 2'-deoxy-N4-(p-anisoyl)cytidine, pyridinium salt; dC(An) Phosphoramidite precursor; N4-Anisoyl-2'-deoxycytidine 5'-monophosphate pyridinium salt; Protected deoxycytidine monophosphate; p-Anisoyl-dCMP pyridinium salt; N4-(4-Methoxybenzoyl)-2'-deoxycytidine 5'-monophosphate pyridinium
EINECS	Contact for details

Quality Control

Our N(4) Anisoyl-2'-Deoxycytidine 5'-Monophosphate Pyridinium is manufactured under strict quality systems suitable for research and pharmaceutical intermediate applications. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure identity, potency, and consistency. Certificates of Analysis (COA) with full chromatographic data are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed in a desiccated environment to prevent degradation. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 3.0%
Solubility	Soluble in anhydrous acetonitrile, DMF

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.