Description

4-Chloro-3-(Trifluoromethyl)Benzyl Alcohol is a versatile fluorinated aromatic building block of significant importance in advanced organic synthesis. Its molecular structure, featuring both a chloro and a trifluoromethyl substituent, makes it a critical intermediate for creating compounds with enhanced biological activity and specific physicochemical properties. This high-purity intermediate is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for developing new active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon in the research and production of novel active pharmaceutical ingredients (APIs), particularly those targeting central nervous system and metabolic diseases.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides, where the trifluoromethyl group often enhances lipophilicity and metabolic stability.
• Liquid Crystal Materials: Serves as a precursor in the synthesis of fluorinated liquid crystals for advanced display technologies.
• Functional Polymer Monomer: Incorporated into specialty polymers to impart unique chemical resistance, thermal stability, or surface properties.
• Organic Synthesis Building Block: Utilized in cross-coupling reactions, nucleophilic substitutions, and oxidation reactions to construct complex molecular architectures in medicinal chemistry.

Basic Information

Product Name	4-Chloro-3-(Trifluoromethyl)Benzyl Alcohol
CAS No.	65735-71-9
Molecular Formula	C8H6ClF3O
Molecular Weight	210.58 g/mol
Synonyms	α-(Trifluoromethyl)-4-chloro-m-benzyl alcohol; (4-Chloro-3-(trifluoromethyl)phenyl)methanol; 1-(Chloromethyl)-2-(trifluoromethyl)benzene-4-ol; 4-Chloro-α,α,α-trifluoro-m-tolyl alcohol; 3-Trifluoromethyl-4-chlorobenzyl alcohol; 4-Chloro-3-trifluoromethylbenzenemethanol; Benzenemethanol, 4-chloro-3-(trifluoromethyl)-
EINECS	265-896-8

Quality Control

Our 4-Chloro-3-(Trifluoromethyl)Benzyl Alcohol is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistent quality suitable for sensitive synthetic applications. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The container should be kept tightly sealed to minimize exposure to moisture and air.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Individual impurity ≤ 0.5%, Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.