Description

4-Hydroxyphenylretinamide is a synthetic retinoid derivative, a compound of significant interest in advanced pharmaceutical research and development. Its value lies in its potential as a targeted therapeutic agent, offering a promising avenue for modulating cellular processes. This product is primarily needed by research institutions, pharmaceutical companies, and biotechnology firms engaged in the development of novel treatments for oncology and dermatology.

Application

• Pharmaceutical Research & Development: A key intermediate or active pharmaceutical ingredient (API) in the synthesis of novel retinoid-based therapeutics.
• Oncology Research: Investigated for its potential anti-proliferative and pro-apoptotic effects in various cancer cell line studies.
• Dermatology Research: Studied for applications in treating skin disorders such as acne, psoriasis, and photoaging due to its retinoid activity.
• Biochemical Research: Used as a reference standard or probe in studies of retinoid receptor (RAR/RXR) signaling pathways and gene expression.
• Preclinical Studies: Employed in animal models to evaluate pharmacokinetics, efficacy, and safety profiles of new drug candidates.

Basic Information

Product Name	4-Hydroxyphenylretinamide
CAS No.	65646-68-6
Molecular Formula	C26H33NO2
Molecular Weight	391.55 g/mol
Synonyms	4-HPR; Fenretinide; N-(4-Hydroxyphenyl)retinamide; 4-Hydroxyphenylretinamide; Retinoic acid 4-hydroxyphenylamide; N-(4-Hydroxyphenyl)-all-trans-retinamide; NSC 374551; AHR 5333
EINECS	Contact for details

Quality Control

Our 4-Hydroxyphenylretinamide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for research and development applications. Certificates of Analysis (COA) with detailed specifications are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at a controlled room temperature (15-25°C) to minimize oxidation and ensure long-term stability. Keep the container in a dry, cool, and well-ventilated area.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (HPLC/IR)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.