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Triacetyl Uridine CAS NO 65499-40-3


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CAS No.:65499-40-3

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

Triacetyl Uridine is a protected nucleoside derivative where the hydroxyl groups of the ribose sugar are acetylated, enhancing its stability and lipophilicity. This modification is crucial for its primary role as a key pharmaceutical intermediate in the synthesis of complex nucleoside analogs and prodrugs. It is essential for research and manufacturing in the pharmaceutical, biotechnology, and life science sectors, particularly for developing antiviral and anticancer therapeutics.

Application

  • Pharmaceutical Intermediate: A critical building block for the synthesis of novel nucleoside-based antiviral and anticancer drugs.
  • Biochemical Research: Used in oligonucleotide synthesis and as a substrate for studying enzyme kinetics and metabolic pathways.
  • Prodrug Development: The acetyl groups facilitate membrane permeability, making it a valuable precursor for prodrug strategies to enhance drug delivery.
  • Reference Standard: Serves as a high-purity analytical standard in quality control laboratories for method development and validation.
  • Cosmetic & Nutraceutical Ingredients: Investigated for use in advanced skincare formulations and dietary supplements targeting cellular health.

Basic Information

Item Detail
Product Name Triacetyl Uridine
CAS No. 65499-40-3
Molecular Formula C15H18N2O9
Molecular Weight 370.31 g/mol
Synonyms 2',3',5'-Tri-O-acetyluridine; Uridine 2',3',5'-triacetate; 1-[(2R,3R,4R,5R)-3,4-Diacetyloxy-5-(acetyloxymethyl)oxolan-2-yl]pyrimidine-2,4-dione; 2',3',5'-Triacetyluridine; TRIACETYLURIDINE; Uridine triacetate
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Quality Control

Our Triacetyl Uridine is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation by IR and NMR spectroscopy, to ensure it meets the high standards required for pharmaceutical intermediates. A Certificate of Analysis (COA) detailing all test results is provided with each shipment to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent product degradation.

Specification

Item Specification
Appearance White to off-white crystalline powder
Identification (IR) Conforms to structure
Assay (HPLC) ≥ 98.0%
Water Content (KF) ≤ 1.0%
Residue on Ignition ≤ 0.1%
Heavy Metals ≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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