Description

8-Butylaminoadenosine is a chemically modified nucleoside analog, specifically an adenosine derivative with a butylamino substituent at the 8-position. This structural modification is significant for its role as a potent and selective agonist for adenosine receptors, particularly the A1 subtype, making it a valuable tool in pharmacological research and drug discovery. It is primarily utilized by pharmaceutical R&D laboratories, academic research institutions, and biotechnology companies focused on neuroscience, cardiology, and metabolic disorders.

Application

• Pharmacological Research: A key reference standard and selective agonist for studying adenosine A1 receptor signaling pathways and physiology.
• Drug Discovery & Development: Serves as a critical intermediate or lead compound in the synthesis of novel therapeutics targeting cardiovascular and neurological conditions.
• Biochemical Assays: Used in high-throughput screening (HTS) and in vitro assays to evaluate receptor binding affinity and functional activity.
• Academic Research: Employed in university and institutional labs for fundamental studies on purinergic signaling, neuroprotection, and cardiac function.
• Reference Standard: Provides a high-purity benchmark for analytical method development, validation, and quality control in API manufacturing.

Basic Information

Product Name	8-Butylaminoadenosine
CAS No.	65456-84-0
Molecular Formula	C14H22N6O4
Molecular Weight	338.37 g/mol
Synonyms	8-(Butylamino)adenosine; N6-Butyladenosine (ambiguous, verify structure); 8-BA; BAA; Adenosine, 8-(butylamino)-; 8-N-Butylaminoadenosine; 8-Butylaminoadenosine; 8-(n-Butylamino)adenosine
EINECS	Contact for details

Quality Control

Our 8-Butylaminoadenosine is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and residual solvent analysis. A Certificate of Analysis (COA) detailing all specifications and test results is provided to ensure traceability and compliance with research-grade standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); the container must be kept tightly sealed in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.