Description

6-Azidohexanoic Acid Ethyl Ester is a versatile bifunctional organic compound featuring both an azide group and an ester moiety. This unique structure makes it a valuable click chemistry reagent and a crucial building block for synthesizing complex molecules via the Huisgen 1,3-dipolar cycloaddition reaction. It is primarily used by researchers and manufacturers in the pharmaceutical, bioconjugation, and materials science industries for the development of new drugs, polymers, and labeled biomolecules.

Application

• Click Chemistry Reagent: A key precursor for copper-catalyzed azide-alkyne cycloaddition (CuAAC) to create triazole linkages in drug discovery and bioconjugation.
• Pharmaceutical Intermediate: Used in the synthesis of active pharmaceutical ingredients (APIs) and prodrugs, particularly for introducing functionalized alkyl chains.
• Polymer & Materials Science: Serves as a monomer or cross-linking agent for creating functionalized polymers, hydrogels, and smart materials with tailored properties.
• Bioconjugation & Probe Synthesis: Facilitates the labeling of proteins, antibodies, and other biomolecules with fluorescent dyes, drugs, or other reporter groups.
• Chemical Biology Tool: Employed in activity-based protein profiling (ABPP) and the development of chemical probes to study biological processes.
• Agrochemical Research: Acts as an intermediate in the synthesis of novel herbicides, fungicides, and plant growth regulators.

Basic Information

Product Name	6-Azidohexanoic Acid Ethyl Ester
CAS No.	65374-10-9
Molecular Formula	C8H15N3O2
Molecular Weight	185.22 g/mol
Synonyms	Ethyl 6-Azidohexanoate; 6-Azidohexanoic Acid Ethyl Ester; Ethyl 6-Azidocaproate; 6-Azidocaproic Acid Ethyl Ester; Azido-PEG1-C2-ethyl ester; 5-Azidopentylacetic Acid Ethyl Ester; Ethyl 5-(Azidomethyl)pentanoate; 1-Azido-5-ethoxycarbonylpentane
EINECS	Contact for details

Quality Control

Our 6-Azidohexanoic Acid Ethyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and IR spectroscopy, to ensure high purity and consistency. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment to support your R&D and cGMP manufacturing needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at 2-8°C under an inert atmosphere (e.g., nitrogen or argon) due to its easily oxidized and highly volatile nature. Keep away from heat, sparks, open flames, and incompatible materials such as strong reducing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.