Description

2'-Deoxypseudoisocytidine is a modified nucleoside analog of significant interest in advanced biochemical and pharmaceutical research. This compound serves as a crucial building block and research tool in the development of oligonucleotide-based therapeutics and diagnostic probes. It is primarily utilized by researchers and manufacturers in the fields of nucleic acid chemistry, antisense technology, and medicinal chemistry. The unique structural properties of this analog make it valuable for studying and modulating biological processes at the genetic level.

Application

• Oligonucleotide Synthesis: A key monomer for the solid-phase synthesis of modified DNA and RNA strands for research and therapeutic applications.
• Antisense & siRNA Development: Used to create nucleoside-modified antisense oligonucleotides and small interfering RNAs (siRNAs) to enhance stability and target specificity.
• Medicinal Chemistry & Drug Discovery: Serves as a critical intermediate in the research and development of novel antiviral and anticancer nucleoside analogs.
• Biochemical Research: Employed as a substrate or inhibitor in enzymatic studies to investigate polymerase activity and nucleic acid metabolism.
• Diagnostic Probe Design: Incorporated into nucleic acid probes to improve hybridization properties and detection sensitivity in diagnostic assays.
• Academic & Institutional Research: Used in university and institutional labs for fundamental studies in genetics, molecular biology, and chemical biology.

Basic Information

Product Name	2'-Deoxypseudoisocytidine
CAS No.	65358-18-1
Molecular Formula	C9H13N3O4
Molecular Weight	227.22 g/mol
Synonyms	2'-Deoxy-ψ-isocytidine; Pseudoisocytidine, 2'-deoxy-; 1-(2-Deoxy-β-D-erythro-pentofuranosyl)-4-amino-2(1H)-pyrimidinone; 4-Amino-1-(2-deoxy-β-D-ribofuranosyl)-2(1H)-pyrimidinone; d-ψ-C; 2'-dPsiC; 2'-Deoxy-pseudoisocytidine
EINECS	Contact for details

Quality Control

Our 2'-Deoxypseudoisocytidine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, NMR for structural confirmation, and mass spectrometry for identity verification, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) with detailed chromatographic data are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.