Description

1,3-Dimethyl-2'-Deoxypseudouridine is a chemically modified nucleoside analog of significant interest in advanced pharmaceutical research and development. This compound matters as a key building block for the synthesis of novel oligonucleotides and therapeutic agents, offering enhanced stability and specific binding properties. It is primarily needed by research institutions and pharmaceutical companies engaged in the development of next-generation antiviral drugs, mRNA therapeutics, and diagnostic probes.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel nucleoside-based antiviral and anticancer agents.
• Oligonucleotide Synthesis: Used as a modified monomer to introduce specific properties into synthetic DNA/RNA strands for therapeutic and diagnostic applications.
• Biochemical Research: Serves as a tool compound for studying enzyme mechanisms, nucleic acid interactions, and metabolic pathways.
• Probe Development: Employed in the creation of labeled nucleotides for use in hybridization assays and next-generation sequencing technologies.
• mRNA Technology: Potential application in the modification of mRNA constructs to enhance stability and translational efficiency for vaccine and therapeutic development.

Basic Information

Product Name	1,3-Dimethyl-2'-Deoxypseudouridine
CAS No.	65358-16-9
Molecular Formula	C11H16N2O5
Molecular Weight	256.26 g/mol
Synonyms	1,3-Dimethyl-2'-deoxy-5-ribosyluracil; 1,3-Dimethyl-2'-deoxy-pseudouridine; 2'-Deoxy-1,3-dimethylpseudouridine; 5-(2-Deoxy-β-D-ribofuranosyl)-1,3-dimethyluracil; 1,3-Dimethyl-2'-deoxy-ψ-uridine; DM-dψ; Pseudouridine, 2'-deoxy-1,3-dimethyl-
EINECS	Contact for details

Quality Control

Our 1,3-Dimethyl-2'-Deoxypseudouridine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the high standards required for pharmaceutical research. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.