Description

Pseudothymidine is a synthetic nucleoside analog of significant interest in advanced pharmaceutical research and development. This compound serves as a crucial building block and intermediate in the synthesis of novel therapeutic agents, particularly in the fields of antiviral and anticancer drug discovery. Key industries that utilize this high-purity intermediate include pharmaceutical R&D, biotechnology, and specialty fine chemical manufacturing for life science applications.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel nucleoside-based antiviral and anticancer drug candidates.
• Biochemical Research: Used as a modified nucleoside in oligonucleotide synthesis for studying DNA/RNA structure, function, and enzyme mechanisms.
• Antiviral Pro-drug Development: Serves as a core scaffold for developing prodrugs targeting viral polymerases.
• Medicinal Chemistry: Employed in structure-activity relationship (SAR) studies to optimize the potency and selectivity of therapeutic compounds.
• Reference Standard: Used as an analytical standard in quality control laboratories for method development and validation.
• Academic Research: Utilized in university and institutional labs for fundamental research in chemical biology and nucleic acid chemistry.

Basic Information

Product Name	Pseudothymidine
CAS No.	65358-15-8
Molecular Formula	C10H14N2O5
Molecular Weight	242.23 g/mol
Synonyms	1-(2-Deoxy-β-D-ribofuranosyl)-5-methyl-2,4(1H,3H)-pyrimidinedione; 5-Methyl-2'-deoxyuridine; 5-Methyldeoxyuridine; dT; Thymidine (common misnomer, but structurally distinct); Pseudothymine deoxyriboside; 2'-Deoxy-5-methyluridine; NSC 403169
EINECS	Contact for details

Quality Control

Our Pseudothymidine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and tests for residual solvents and moisture content. We provide full traceability and Certificates of Analysis (COA) are available for all shipments, ensuring compliance with research and development grade specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept in a dry environment. For long-term storage, consider desiccant use and inert atmosphere to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.