Description

Endralazine is a high-purity pharmaceutical intermediate and active pharmaceutical ingredient (API) with significant therapeutic potential. This compound is valued for its specific pharmacological activity, making it a critical component in advanced pharmaceutical research and development. It is primarily utilized by pharmaceutical manufacturers and research institutions engaged in the development of novel therapeutic agents, particularly within the cardiovascular and central nervous system (CNS) drug sectors.

Application

• Pharmaceutical API Synthesis: Serves as a key building block or the final active ingredient in the manufacture of prescription medications.
• Cardiovascular Research: Used in preclinical and clinical research for developing new antihypertensive and vasodilatory agents.
• Neurological/CNS Drug Development: Applied in studies targeting conditions related to the central nervous system.
• Reference Standard: Employed as a high-purity analytical standard for quality control and method validation in pharmaceutical laboratories.
• Process Chemistry & Scale-Up: Utilized in process optimization and pilot-scale production for new drug candidates.
• Academic & Institutional Research: Supports chemical and pharmacological studies in university and institutional settings.

Basic Information

Product Name	Endralazine
CAS No.	65322-72-7
Molecular Formula	C₁₃H₁₅N₅
Molecular Weight	241.29 g/mol
Synonyms	Endralazine; 1,4-Dihydro-1-[(6-methyl-3-pyridazinyl)hydrazono]-2,4,6(1H,3H,5H)-pyrimidinetrione; 6-Methyl-3-hydrazinopyridazine phthalazine; SQ 15860; SQ-15860; 1,4-Dihydro-1-[(6-methyl-3-pyridazinyl)hydrazinylidene]-2,4,6(1H,3H,5H)-pyrimidinetrione
EINECS	Contact for details

Quality Control

Our Endralazine is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including identification, assay, and impurity profiling via techniques such as HPLC, IR, and NMR. A Certificate of Analysis (COA) detailing all test results is provided with every shipment to guarantee compliance with your specifications and support regulatory filings.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Related Substances (HPLC)	Total impurities ≤2.0% Any single impurity ≤0.5%
Loss on Drying	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.