Description

2'-o-Methyl-N1-Methyl Inosine is a chemically modified nucleoside derivative, specifically a methylated analog of inosine. This compound is of significant interest in pharmaceutical research and development due to its role as a key intermediate or building block in the synthesis of novel therapeutic agents. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of nucleoside-based drugs, including potential antiviral and anticancer therapies. The precise modification of the ribose and base moieties allows for fine-tuning of biological activity and metabolic stability.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of modified nucleoside analogs for antiviral and anticancer drug discovery programs.
• Biochemical Research: Used as a substrate or inhibitor in enzymatic studies to investigate RNA modification pathways and nucleoside metabolism.
• Pro-drug Development: Serves as a precursor molecule for creating more bioavailable or targeted pro-drug formulations.
• Antiviral Agent Synthesis: Potential intermediate in the development of nucleoside reverse transcriptase inhibitors (NRTIs) or other antiviral compounds.
• Labeled Compound Synthesis: Can be used as a starting point for synthesizing isotopically labeled (e.g., 13C, 15N) nucleosides for metabolic tracing studies.
• Oligonucleotide Chemistry: May be incorporated into synthetic oligonucleotides to study structure-activity relationships and enhance nuclease resistance.

Basic Information

Item	Details
Product Name	2'-o-Methyl-N1-Methyl Inosine
CAS No.	65150-69-8
Molecular Formula	C11H14N4O5
Molecular Weight	282.25 g/mol
Synonyms	1-Methyl-2'-O-methylinosine; 2'-O-Methyl-1-methylinosine; N1-Methyl-2'-O-methylinosine; 9-[(2R,3R,4R,5R)-3,4-Dihydroxy-5-(hydroxymethyl)-3-methyloxolan-2-yl]-3,9-dihydro-1-methyl-6H-purin-6-one; 1-Methyl-2'-O-methyl-9H-purin-6-ol; Inosine, 1-methyl-2'-O-methyl-
EINECS	Contact for details

Quality Control

Our 2'-o-Methyl-N1-Methyl Inosine is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity assessment and NMR for structural confirmation, to ensure it meets the high standards required for research and pharmaceutical applications. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting identity, purity, and impurity profiles. We support compliance with cGMP and ICH guidelines for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.