Description

2-(3,4-Dichlorophenyl)-1,1,1,3,3,3-Hexafluoro-Propan-2-Ol is a specialized fluorinated alcohol derivative, serving as a critical advanced intermediate in modern synthetic chemistry. Its value lies in the unique combination of a hexafluoro-isopropanol moiety and a dichlorinated phenyl ring, which imparts significant lipophilicity and metabolic stability to target molecules. This compound is primarily sought by research and development teams in the pharmaceutical and agrochemical sectors for the synthesis of novel active ingredients, including potential herbicides, fungicides, and pharmaceutical candidates.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and metabolic diseases.
• Agrochemical Synthesis: Core precursor in the development of next-generation herbicides and fungicides, leveraging the dichlorophenyl group for enhanced bioactivity.
• Material Science Research: Used in the creation of specialty monomers for fluorinated polymers, contributing to materials with unique surface properties and chemical resistance.
• Ligand and Catalyst Development: Serves as a sophisticated precursor for chiral ligands and organocatalysts used in asymmetric synthesis.
• Life Sciences & Biochemical Research: Employed in medicinal chemistry programs for structure-activity relationship (SAR) studies and molecular probe development.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for scale-up and process development of client-specific molecules.

Basic Information

Item	Details
Product Name	2-(3,4-Dichlorophenyl)-1,1,1,3,3,3-Hexafluoro-Propan-2-Ol
CAS No.	65072-48-2
Molecular Formula	C9H4Cl2F6O
Molecular Weight	313.03 g/mol
Synonyms	1,1,1,3,3,3-Hexafluoro-2-(3,4-dichlorophenyl)propan-2-ol; 2-(3,4-Dichlorophenyl)hexafluoroisopropanol; 3,4-Dichloro-α-(trifluoromethyl)benzenemethanol, 1,1,1,3,3,3-Hexafluoro-2-(3,4-dichlorophenyl)-2-propanol; Hexafluoro-2-(3,4-dichlorophenyl)isopropanol; α,α-Bis(trifluoromethyl)-3,4-dichlorobenzyl alcohol
EINECS	Contact for details

Quality Control

Every batch of 2-(3,4-Dichlorophenyl)-1,1,1,3,3,3-Hexafluoro-Propan-2-Ol is manufactured and tested under a strict quality management system. Our products undergo rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment to guarantee compliance with your research and development requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after each use to prevent moisture absorption, which may affect product stability and performance.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.