Description

2-Adamantane Isothiocyanate is a specialized organic building block featuring the rigid, three-dimensional adamantane cage functionalized with a reactive isothiocyanate group. This compound matters for its unique structural properties, offering a robust, lipophilic scaffold that can enhance the stability and biological activity of target molecules in advanced research and development. It is primarily needed by pharmaceutical researchers, agrochemical scientists, and material chemists working on novel drug candidates, bioactive agents, and high-performance polymers.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel drug candidates, particularly those targeting neurological disorders or requiring enhanced blood-brain barrier penetration.
• Agrochemical Research: Used in developing new pesticides and herbicides where the adamantane moiety can contribute to improved environmental stability and efficacy.
• Material Science: Acts as a monomer or cross-linking agent in the creation of advanced polymers with high thermal stability and specific mechanical properties.
• Bioconjugation & Probe Synthesis: The reactive isothiocyanate group enables covalent attachment to amines, making it valuable for creating fluorescent probes, affinity labels, and antibody-drug conjugates (ADCs).
• Chemical Biology: Utilized as a tool compound for studying protein interactions and enzyme inhibition due to its ability to modify specific amino acid residues.
• Ligand & Catalyst Development: Employed in designing novel ligands for catalysis or metal-organic frameworks (MOFs), leveraging its rigid geometry.

Basic Information

Product Name	2-Adamantane Isothiocyanate
CAS No.	65068-86-2
Molecular Formula	C11H15NS
Molecular Weight	193.31 g/mol
Synonyms	2-Adamantyl Isothiocyanate; Adamantan-2-yl Isothiocyanate; 2-Isothiocyanatoadamantane; 2-Adamantyl Mustard Oil; NSC 169854; 1-Isothiocyanatoadamantane (common numbering variant); Tricyclo[3.3.1.13,7]decan-2-yl isothiocyanate
EINECS	Contact for details

Quality Control

Our 2-Adamantane Isothiocyanate is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and FTIR, to ensure high purity and consistent performance. Certificates of Analysis (COA) documenting identity, purity, and impurity profiles are available upon request to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.