Description

3,7,23-Trihydroxycholan-24-Oic Acid CAS NO 64937-93-5 is a polyhydroxylated bile acid derivative, a key intermediate in the synthesis of complex steroidal compounds. Its unique hydroxylation pattern makes it a valuable scaffold for pharmaceutical research and development, particularly in the study of metabolic pathways and receptor modulation. This high-purity compound is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and fine chemical sectors.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of novel steroidal drugs and therapeutic agents.
• Biochemical Research: Used as a reference standard and probe in studies of bile acid metabolism, liver function, and nuclear receptor (e.g., FXR) signaling.
• Fine Chemical Synthesis: Serves as a versatile chiral starting material for the preparation of complex, high-value specialty chemicals.
• Metabolite Standard: Employed in analytical laboratories for the identification and quantification of bile acid metabolites in biological samples via LC-MS or HPLC.
• Academic Research: Utilized in university and institutional labs for fundamental research in organic chemistry, medicinal chemistry, and endocrinology.

Basic Information

Product Name	3,7,23-Trihydroxycholan-24-Oic Acid
CAS No.	64937-93-5
Molecular Formula	C₂₄H₄₀O₅
Molecular Weight	408.57 g/mol
Synonyms	3α,7α,23-Trihydroxy-5β-cholan-24-oic Acid; 3α,7α,23-Trihydroxy-5β-cholanic Acid; 23-Hydroxycholic Acid; 3,7,23-Trihydroxycholanic Acid; Hyocholic Acid (isomer); 5β-Cholan-24-oic acid, 3α,7α,23-trihydroxy-; Hyocholic Acid 23-Isomer
EINECS	Contact for details

Quality Control

Our 3,7,23-Trihydroxycholan-24-Oic Acid is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets the high standards required for research and synthesis. Certificates of Analysis (COA) with detailed chromatograms and spectral data are provided to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under inert atmosphere or desiccated conditions after opening to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Specific Optical Rotation	Contact for details
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.