Description

1-Piperidinecarbonyl Chloride, 3-Methyl- (9Ci) is a versatile and highly reactive acid chloride derivative of 3-methylpiperidine. This compound serves as a critical building block in organic synthesis, enabling the efficient introduction of the 3-methylpiperidinecarbonyl moiety into target molecules. It is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and complex intermediates.

Application

• Pharmaceutical Intermediate: Key reagent in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds targeting neurological and metabolic disorders.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides, where the piperidine scaffold is a common structural motif.
• Peptide Mimetics & PROTACs: Employed in medicinal chemistry for constructing peptide-like molecules and proteolysis-targeting chimeras (PROTACs) due to its amide-forming capability.
• Material Science Research: Acts as a monomer or cross-linking agent in the development of specialty polymers with tailored properties.
• Chemical Biology Probes: Utilized to create labeled compounds and molecular probes for studying biological pathways and enzyme functions.
• Custom Synthesis & Contract Manufacturing: A valuable starting material for custom synthesis services catering to R&D and scale-up projects.

Basic Information

Product Name	1-Piperidinecarbonyl Chloride, 3-Methyl- (9Ci)
CAS No.	64920-80-5
Molecular Formula	C7H12ClNO
Molecular Weight	161.63 g/mol
Synonyms	3-Methylpiperidine-1-carbonyl chloride; 3-Methyl-1-piperidinecarbonyl chloride; 1-Chlorocarbonyl-3-methylpiperidine; 3-Methylpiperidine-1-carboxylic acid chloride; 3-Methylpiperidin-1-ylcarbonyl chloride; 3-Methyl-1-piperidylcarbonyl chloride; 3-Methylpiperidine-1-carbonyl chloride (9CI)
EINECS	Contact for details

Quality Control

Our 1-Piperidinecarbonyl Chloride, 3-Methyl- (9Ci) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. Certificates of Analysis (COA) with detailed specifications are provided for every shipment, confirming compliance with customer requirements and industry best practices for fine chemical synthesis.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and reacts with strong acids/organic solvents; therefore, it must be kept under an inert atmosphere (e.g., nitrogen or argon) and away from incompatible materials. Keep the container tightly sealed when not in use.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.