Description

4-Pyridinecarbonyl Chloride, 3-Methyl- (9Ci) CAS NO 64915-79-3 is a versatile and reactive heterocyclic acid chloride derivative, serving as a critical building block in advanced organic synthesis. Its core value lies in enabling the efficient introduction of the 3-methylpyridine-4-carbonyl moiety, a key structural feature for modifying molecular properties. This high-purity intermediate is essential for research chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries who require reliable, high-quality reagents for constructing complex molecules.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in developing kinase inhibitors, receptor modulators, and other small-molecule therapeutics.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides, where the pyridine core contributes to biological activity.
• Ligand and Catalyst Preparation: Serves as a precursor for synthesizing specialized ligands used in homogeneous catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the creation of functional polymers, liquid crystals, and organic electronic materials due to its reactive acid chloride group and aromatic system.
• Custom Chemical Synthesis: A valuable reagent for contract research organizations (CROs) and custom synthesis facilities producing bespoke compounds for client projects.
• Bioconjugation and Probe Development: Facilitates the attachment of reporter groups or linkers to biomolecules in diagnostic and biochemical research.

Basic Information

Product Name	4-Pyridinecarbonyl Chloride, 3-Methyl- (9Ci)
CAS No.	64915-79-3
Molecular Formula	C7H6ClNO
Molecular Weight	155.58 g/mol
Synonyms	3-Methylisonicotinoyl chloride; 3-Methylpyridine-4-carbonyl chloride; 4-Carbonyl chloride-3-methylpyridine; 3-Methyl-4-pyridinecarbonyl chloride; Isonicotinic acid, 3-methyl-, chloride; 3-Picoline-4-carbonyl chloride
EINECS	Contact for details

Quality Control

Every batch of 4-Pyridinecarbonyl Chloride, 3-Methyl- is manufactured and tested under strict quality management systems to ensure consistency and reliability for your synthetic workflows. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing purity, identity, and impurity profiles. Our standard grade meets high-purity research specifications, and we can support development toward cGMP standards for pharmaceutical applications upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and reacts with strong acids/organic solvents; keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) to prevent degradation. Keep away from heat, open flames, and incompatible materials such as bases, alcohols, and amines.

Specification

Item	Specification
Appearance	White to off-white crystalline solid or powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.