Description

3-(4-(9-Acridinylamino)Phenyl)-2-Propenamide Monohydrochloride is a specialized organic compound belonging to the acridine class, known for its role as a key intermediate in advanced pharmaceutical research and development. This compound is valued for its structural properties that make it a crucial building block in the synthesis of novel therapeutic agents, particularly in oncology and targeted drug discovery. It is primarily utilized by research institutions, pharmaceutical R&D laboratories, and fine chemical manufacturers focused on developing innovative small-molecule drugs and biochemical probes.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel acridine-based anticancer agents and experimental therapeutics.
• Biochemical Research: Used as a research chemical for studying DNA intercalation mechanisms and developing fluorescence-based assays.
• Antitumor Agent Development: Serves as a core scaffold for the design and optimization of compounds targeting specific cellular pathways.
• Academic & Contract Research: Employed in university and CRO settings for medicinal chemistry projects and structure-activity relationship (SAR) studies.
• Reference Standard: Can be supplied as a high-purity standard for analytical method development and quality control in API manufacturing.

Basic Information

Product Name	3-(4-(9-Acridinylamino)Phenyl)-2-Propenamide Monohydrochloride
CAS No.	64895-21-2
Molecular Formula	C22H18N3O • HCl
Molecular Weight	383.86 g/mol (Free base: 348.40 g/mol)
Synonyms	9-Acridinamine, N-[4-(2-amino-2-oxoethenyl)phenyl]-, monohydrochloride; Acridinylaminophenylpropenamide hydrochloride; NSC 339004; 3-[4-(9-Acridinylamino)phenyl]-2-propenamide hydrochloride; 9-[(4-Acrylamidophenyl)amino]acridine hydrochloride
EINECS	Contact for details

Quality Control

Our 3-(4-(9-Acridinylamino)Phenyl)-2-Propenamide Monohydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, identity confirmation via IR and NMR spectroscopy, and residual solvent analysis to ensure it meets the stringent requirements for research and development use. A Certificate of Analysis (COA) detailing all test results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. Keep the container tightly sealed when not in use.

Specification

Item	Specification
Appearance	Yellow to orange-yellow powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.