Description

Bromoacetic-2-13C Acid is a stable isotope-labeled derivative of bromoacetic acid, where the carbon-2 position is enriched with the 13C isotope. This precise labeling is critical for applications requiring high-sensitivity detection and accurate metabolic pathway tracing in research. It is an essential building block and tracer molecule for pharmaceutical, agrochemical, and advanced material scientists engaged in isotope dilution mass spectrometry (IDMS), NMR spectroscopy, and kinetic studies.

Application

• Isotope-Labeled Intermediate Synthesis: Serves as a key 13C-labeled precursor in the synthesis of more complex labeled pharmaceuticals and agrochemicals.
• Metabolic Pathway Analysis: Used as a tracer to study biochemical pathways and mechanisms of action in biological systems.
• Quantitative Mass Spectrometry: Employed as an internal standard in Isotope Dilution Mass Spectrometry (IDMS) for the precise quantification of analytes in complex matrices.
• NMR Spectroscopy Studies: Provides a distinct 13C NMR signal for structural elucidation and reaction monitoring in chemical research.
• Chemical Reaction Mechanism Investigation: Utilized to track the fate of specific carbon atoms in organic reaction mechanisms and kinetics.
• Development of Diagnostic Agents: Acts as a starting material for developing isotope-labeled diagnostic probes and imaging agents.

Basic Information

Product Name	Bromoacetic-2-13C Acid
CAS No.	64891-77-6
Molecular Formula	C13CH2BrCOOH
Molecular Weight	138.95 g/mol (for 13C1 isotopologue)
Synonyms	(2-13C)Bromoacetic Acid; Bromoacetic-2-13C Acid; 2-Bromoacetic-2-13C Acid; Bromo(13C)acetic Acid; Carboxy-13C-methyl Bromide; Monobromoacetic-2-13C Acid; NSC 73931-13C; BAA-13C
EINECS	Contact for details

Quality Control

Our Bromoacetic-2-13C Acid is produced and handled under strict quality protocols to ensure isotopic and chemical purity for sensitive research applications. Each batch is analyzed to confirm isotopic enrichment (typically ≥99 atom % 13C) and chemical specifications. Certificates of Analysis (COA) detailing assay, isotopic purity, and impurity profiles are provided and available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and a strong acid/organic solvent; keep the container tightly sealed when not in use and store separately from bases and reactive materials.

Specification

Item	Specification
Appearance	White to off-white crystalline solid
Identification (IR / NMR)	Conforms to structure
Isotopic Purity (13C)	≥99 atom %
Chemical Purity (HPLC)	≥98.0%
Melting Point	49 - 52 °C

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.