Description

Butoconazole is a potent synthetic imidazole derivative widely recognized for its exceptional antifungal properties. This compound is a critical active pharmaceutical ingredient (API) valued for its targeted efficacy against a broad spectrum of pathogenic fungi. It is primarily utilized by pharmaceutical manufacturers and research institutions in the development and production of topical antifungal treatments. Butoconazole CAS NO 64872-76-0 is supplied to meet the stringent quality demands of the global pharmaceutical industry.

Application

• Pharmaceutical API: Primary use as the active ingredient in prescription and over-the-counter topical antifungal creams, ointments, and suppositories.
• Vaginal Antifungal Formulations: Key component in treatments for vulvovaginal candidiasis (yeast infections).
• Dermatological Preparations: Used in creams and solutions for treating cutaneous fungal infections such as tinea corporis, tinea cruris, and tinea pedis.
• Veterinary Medicine: Incorporated into topical antifungal products for animal healthcare.
• Research & Development: Serves as a reference standard and building block in microbiological research and the development of new antifungal agents.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for formulation into final drug products.

Basic Information

Product Name	Butoconazole
CAS No.	64872-76-0
Molecular Formula	C19H15Cl3N2S
Molecular Weight	411.76 g/mol
Synonyms	Butoconazole Nitrate; (±)-1-[4-(4-Chlorophenyl)-2-[(2,6-dichlorophenyl)thio]butyl]-1H-imidazole; RS-35887; Femstat; Gynazole-1; Butoconazol; Butoconazolum
EINECS	Contact for details

Quality Control

Our Butoconazole is manufactured under strict quality management systems to ensure it meets the high standards required for pharmaceutical applications. Each batch is subjected to comprehensive analytical testing, including identification, assay, and impurity profiling via HPLC, to confirm compliance with established specifications. A Certificate of Analysis (COA) documenting purity, related substances, and other critical parameters is provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept in a dry environment to maintain stability and potency.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.