Description

5-Oxazolecarbonyl Chloride, 2,3-Dihydro-3-Methyl-2-Oxo- (9Ci) is a versatile and highly reactive heterocyclic acid chloride derivative, serving as a critical building block in advanced organic synthesis. Its primary value lies in its ability to efficiently introduce the 5-oxazolecarbonyl moiety into target molecules, enabling the construction of complex pharmacophores and functional materials. This compound is essential for research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries who require high-purity intermediates for developing new active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, infectious diseases, and metabolic conditions.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides, where the oxazole ring contributes to biological activity.
• Peptide Mimetics & Bioconjugation: Employed to create peptide analogs and for the site-specific modification of biomolecules to enhance stability or confer new properties.
• Material Science Research: Acts as a monomer or cross-linking agent in the development of specialty polymers, coatings, and functional organic materials.
• Chemical Biology Probes: Utilized to synthesize activity-based probes and molecular tags for studying enzyme function and cellular pathways.
• Scale-Up Process Chemistry: Serves as a reliable intermediate for the kilogram-scale production of target compounds under Good Manufacturing Practice (GMP) guidelines where applicable.

Basic Information

Product Name	5-Oxazolecarbonyl Chloride, 2,3-Dihydro-3-Methyl-2-Oxo- (9Ci)
CAS No.	64843-29-4
Molecular Formula	C5H4ClNO3
Molecular Weight	161.54 g/mol
Synonyms	3-Methyl-2-oxo-2,3-dihydrooxazole-5-carbonyl chloride; 2,3-Dihydro-3-methyl-2-oxo-5-oxazolecarbonyl chloride; 5-Oxazolecarbonyl chloride, 2,3-dihydro-3-methyl-2-oxo-; 3-Methyl-2-oxo-2,3-dihydro-1,3-oxazole-5-carbonyl chloride; 64843-29-4; 3-Methyl-2-oxo-2,5-dihydrooxazole-5-carbonyl chloride
EINECS	Contact for details

Quality Control

Our 5-Oxazolecarbonyl Chloride, 2,3-Dihydro-3-Methyl-2-Oxo- (9Ci) is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via FT-IR and NMR spectroscopy, to ensure it meets the high standards required for research and commercial synthesis. Certificates of Analysis (COA) detailing batch-specific results are provided and available upon request to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature and reactivity as an acid chloride, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from strong bases, oxidizing agents, and sources of moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline solid or powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.