Description

1H-Indole-2-Carbonylchloride,4-Methyl-(9Ci) CAS NO 64679-00-1 is a specialized, high-purity chemical building block belonging to the indole class of heterocyclic compounds. This compound is a critical intermediate for the synthesis of more complex molecules, offering a reactive acid chloride group for efficient amide bond formation and other derivatizations. It is primarily utilized by research and development chemists in the pharmaceutical and agrochemical industries for creating novel active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly those targeting neurological and oncological pathways.
• Agrochemical Research: Used in the development of new pesticides, herbicides, and plant growth regulators with enhanced efficacy.
• Organic Synthesis Reagent: Serves as a versatile reagent for introducing the 4-methylindole-2-carbonyl moiety into complex molecular architectures.
• Material Science Precursor: Employed in the creation of specialty polymers and advanced organic electronic materials.
• Bioconjugation Chemistry: Facilitates the labeling and modification of biomolecules for diagnostic and research applications.
• Academic & Contract Research: Essential for medicinal chemistry programs and custom synthesis projects in university and CRO laboratories.

Basic Information

Product Name	1H-Indole-2-Carbonylchloride,4-Methyl-(9Ci)
CAS No.	64679-00-1
Molecular Formula	C10H8ClNO
Molecular Weight	193.63 g/mol
Synonyms	4-Methyl-1H-indole-2-carbonyl chloride; 4-Methylindole-2-carbonyl chloride; 1H-Indole-2-carbonyl chloride, 4-methyl-; 4-Methyl-1H-indole-2-carboxylic acid chloride; 64679-00-1; 4-Methylindol-2-carbonyl chloride
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. Each batch of 1H-Indole-2-Carbonylchloride,4-Methyl-(9Ci) is analyzed using advanced techniques including HPLC, NMR, and IR spectroscopy to confirm identity and purity. Certificates of Analysis (COA) with detailed chromatographic data are available upon request. We adhere to strict in-process controls to guarantee batch-to-batch consistency for your research and development needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature and reactivity as an acid chloride, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent decomposition. Keep away from strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0% (Area %)
Water Content (KF)	≤ 0.5%
Solubility	Soluble in common organic solvents (DMF, THF, DCM)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.