Description

Paris Saponin I CAS NO 64652-21-7 is a high-purity, bioactive steroidal saponin compound derived from the rhizomes of *Paris polyphylla*. This specialized phytochemical is valued for its significant biological activity and serves as a critical reference standard and active ingredient in advanced research and development. It is primarily utilized by the pharmaceutical, nutraceutical, and academic research sectors for applications in drug discovery, formulation studies, and biochemical analysis.

Application

• Pharmaceutical Reference Standard: Used as a certified reference material (CRM) for the quality control and standardization of herbal extracts and finished pharmaceutical products.
• Drug Discovery & Research: Serves as a key intermediate or active pharmaceutical ingredient (API) in preclinical studies investigating anti-tumor, anti-inflammatory, and antimicrobial agents.
• Natural Product Isolation: Acts as a marker compound in the extraction, purification, and chromatographic analysis (HPLC, TLC) of steroidal saponins from plant materials.
• Biochemical Research: Employed in cell-based assays and mechanistic studies to explore signaling pathways and biological functions.
• Nutraceutical Formulation: Incorporated into high-end dietary supplements where standardized bioactive components are required for consistent efficacy.
• Cosmetic Actives: Used in the development of cosmetic formulations for its potential skin-beneficial properties.

Basic Information

Product Name	Paris Saponin I
CAS No.	64652-21-7
Molecular Formula	C39H62O12
Molecular Weight	722.9 g/mol
Synonyms	Polyphyllin I; Polyphyllin A; Paris saponin A; Pennogenin 3-O-α-L-rhamnopyranosyl-(1→2)-[α-L-rhamnopyranosyl-(1→4)]-β-D-glucopyranoside; (25R)-Spirost-5-en-3β-ol 3-O-α-L-rhamnopyranosyl-(1→2)-[α-L-rhamnopyranosyl-(1→4)]-β-D-glucopyranoside; Dwarf Lilyturf Tuber Saponin I; Chonglou Saponin I
EINECS	Contact for details

Quality Control

Our Paris Saponin I is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation (IR, MS), to ensure it meets the high standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing purity, residual solvents, and heavy metals is provided with every shipment to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. This product is hygroscopic (moisture-sensitive) and light-sensitive; prolonged exposure to air, moisture, or light should be avoided to maintain stability and potency.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 2.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm
Residual Solvents	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.