Description

2-Pyridinecarbonyl Chloride, 3-Methyl- (9Ci) is a versatile and reactive heterocyclic acid chloride derivative, serving as a critical building block in advanced organic synthesis. Its primary value lies in its ability to introduce the 3-methylpicolinoyl moiety, enabling the construction of complex molecules with tailored properties. This high-purity intermediate is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries developing new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key synthon for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in kinase inhibitor and central nervous system (CNS) drug discovery.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides, where the picolinoyl group enhances biological activity.
• Ligand and Catalyst Preparation: Acts as a precursor for creating specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Polymer and Material Science: Employed to modify polymer backbones or create functional monomers, imparting specific chemical or physical characteristics to advanced materials.
• Peptide Mimetics and Bioconjugation: Useful in medicinal chemistry for creating peptide analogs and for bioconjugation techniques in probe and drug delivery system development.
• Research and Development: A valuable reagent in academic and industrial R&D labs for exploring new synthetic pathways and compound libraries.

Basic Information

Product Name	2-Pyridinecarbonyl Chloride, 3-Methyl- (9Ci)
CAS No.	64588-88-1
Molecular Formula	C7H6ClNO
Molecular Weight	155.58 g/mol
Synonyms	3-Methylpicolinoyl Chloride; 3-Methylpyridine-2-carbonyl Chloride; 2-Carbonyl Chloride-3-methylpyridine; 3-Methyl-2-pyridinecarbonyl Chloride; 3-Methylpyridine-2-carboxylic Acid Chloride; 3-Methylpicolinic Acid Chloride
EINECS	Contact for details

Quality Control

Our 2-Pyridinecarbonyl Chloride, 3-Methyl- (9Ci) is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and NMR/IR for structural confirmation, to ensure it meets the high standards required for sensitive synthetic applications. A detailed Certificate of Analysis (COA) is provided with every shipment, guaranteeing traceability and consistent quality for your R&D and production needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). Due to its hygroscopic and moisture-sensitive nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent decomposition. Keep away from strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.