Description

1H-Pyrrole-2-Carbonyl Chloride, 4,5-Dichloro- (9Ci) is a highly reactive and versatile heterocyclic building block, specifically a dichlorinated pyrrole derivative activated by an acid chloride functional group. This compound is essential for the synthesis of complex molecules, enabling the efficient introduction of the 4,5-dichloropyrrole moiety into target structures. It is primarily utilized by researchers and manufacturers in the pharmaceutical and agrochemical industries for developing novel active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: A key synthon for constructing pyrrole-based drug candidates, including potential kinase inhibitors, antimicrobials, and other bioactive molecules.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides where the dichloropyrrole structure confers specific biological activity.
• Material Science Research: Serves as a precursor for functional polymers, dyes, and organic electronic materials due to its electron-rich heterocyclic core.
• Chemical Biology & Proteomics: Employed as a reactive handle for labeling or modifying biomolecules in probe development.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom chemical synthesis services catering to R&D and scale-up projects.

Basic Information

Item	Detail
Product Name	1H-Pyrrole-2-Carbonyl Chloride, 4,5-Dichloro- (9Ci)
CAS No.	64566-93-4
Molecular Formula	C5H2Cl3NO
Molecular Weight	198.43 g/mol
Synonyms	4,5-Dichloro-1H-pyrrole-2-carbonyl chloride; 4,5-Dichloropyrrole-2-carbonyl chloride; 2-(Chlorocarbonyl)-4,5-dichloropyrrole; 4,5-Dichloro-2-pyrrolecarbonyl chloride; 4,5-Dichloro-1H-pyrrole-2-carboxylic acid chloride
EINECS	Contact for details

Quality Control

Our production of 1H-Pyrrole-2-Carbonyl Chloride, 4,5-Dichloro- (9Ci) adheres to stringent quality protocols to ensure batch-to-batch consistency and high purity for sensitive synthetic applications. Each lot undergoes comprehensive analytical characterization, including HPLC, NMR, and IR spectroscopy. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic and moisture-sensitive nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) to prevent decomposition. Recommended storage temperature is 2-8°C for long-term stability.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.