Description

Thymidine, 3-Chloro- CAS NO 64398-17-0 is a halogenated nucleoside derivative, a key building block in organic synthesis and pharmaceutical research. This modified nucleoside is valued for its role as a versatile intermediate in the development of novel antiviral and anticancer agents, particularly nucleotide analogs. It is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and fine chemical sectors engaged in nucleoside chemistry and prodrug development.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of antiviral and anticancer nucleotide analogs.
• Biochemical Research: Used as a modified substrate in enzymatic studies and nucleic acid metabolism research.
• Pro-drug Development: Serves as a key building block for creating targeted nucleoside pro-drugs to enhance therapeutic efficacy.
• Organic Synthesis: Employed as a specialized reagent for introducing chlorinated nucleoside motifs into complex molecules.
• Life Sciences: Utilized in the development of molecular probes and diagnostic agents.

Basic Information

Product Name	Thymidine, 3-Chloro-
CAS No.	64398-17-0
Molecular Formula	C10H13ClN2O5
Molecular Weight	276.67 g/mol
Synonyms	3-Chlorothymidine; 1-((2R,4S,5R)-4-Hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-5-chloro-2,4(1H,3H)-pyrimidinedione; 5-Chloro-1-((2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)pyrimidine-2,4(1H,3H)-dione; 5-Chloro-2'-deoxyuridine (Note: 5-Chloro-2'-deoxyuridine is a closely related isomer, often used synonymously in literature); 5-Cl-dThd; Chlorodeoxythymidine
EINECS	Contact for details

Quality Control

Our Thymidine, 3-Chloro- is produced under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets the high standards required for research and synthesis. Certificates of Analysis (COA) detailing purity, impurities, and physical characteristics are available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.