Description

2-Iodo-n-[2-[(2-Iodoacetyl)Amino]Phenyl]Acetamide is a specialized bifunctional iodoacetamide derivative, a key building block in chemical synthesis and bioconjugation. This compound matters for its ability to act as a potent alkylating agent, specifically targeting thiol groups, which is critical for modifying proteins, peptides, and other biomolecules. It is primarily needed by researchers and manufacturers in the pharmaceutical, biotechnology, and life sciences sectors for developing targeted therapeutics, diagnostic probes, and advanced research reagents.

Application

• Bioconjugation Reagent: For site-specific labeling of cysteine residues in proteins and antibodies for drug-antibody conjugates (ADCs) and diagnostic assays.
• Chemical Crosslinking: Used to create covalent linkages between biomolecules or to immobilize them onto solid supports.
• Pharmaceutical Intermediate: Serves as a critical synthon in the synthesis of more complex, biologically active molecules and potential drug candidates.
• Proteomics Research: Employed in activity-based protein profiling (ABPP) and other studies to investigate enzyme function and protein interactions.
• Peptide Modification: Enables the selective introduction of iodine or other functional groups into synthetic peptides.
• Material Science: Potential use in the surface functionalization of polymers and nanomaterials for biomedical applications.

Basic Information

Product Name	2-Iodo-n-[2-[(2-Iodoacetyl)Amino]Phenyl]Acetamide
CAS No.	64381-85-7
Molecular Formula	C10H10I2N2O2
Molecular Weight	443.99 g/mol
Synonyms	N-(2-[(2-Iodoacetamido)phenyl]-2-iodoacetamide; 2,2'-Iminodiacetic Acid Bis(2-iodoethyl) Ester (related structure); Bis(2-iodoacetyl)-o-phenylenediamine; Iodoacetamide Phenyl Derivative; IAA-Phe-NH-IAA; Bifunctional Iodoacetamide Crosslinker; o-Phenylenebis(2-iodoacetamide)
EINECS	Contact for details

Quality Control

Our 2-Iodo-n-[2-[(2-Iodoacetyl)Amino]Phenyl]Acetamide is produced under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation by NMR and IR spectroscopy, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) detailing all specifications are provided and available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its light-sensitive nature, handling should be performed under subdued light or in amber glass containers to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Residual Solvents	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.