Description

2'-Deoxy-5-Propyl-5'Uridylic Acid is a chemically modified nucleoside monophosphate derivative of uridine, where a propyl group is substituted at the 5-position of the uracil base. This specific modification is crucial for researchers developing novel nucleotide analogs with tailored biological activity and physicochemical properties. It serves as a key synthetic intermediate and research tool for pharmaceutical chemists and biochemists in the fields of antiviral drug discovery, oligonucleotide synthesis, and enzyme mechanism studies.

Application

• Pharmaceutical Intermediate: A critical building block in the research and development of novel nucleoside-based antiviral and anticancer therapeutics.
• Biochemical Research: Used as a substrate or inhibitor in enzymatic studies to investigate the function of kinases, polymerases, and other nucleotide-processing enzymes.
• Oligonucleotide Synthesis: Serves as a modified phosphoramidite precursor for the solid-phase synthesis of oligonucleotides with specific base modifications for diagnostic probes or aptamers.
• Metabolic Pathway Studies: Employed as a tracer or analog to study nucleotide salvage pathways and intracellular metabolism in cell culture models.
• Reference Standard: Used as a high-purity analytical standard in quality control laboratories for method development and validation in pharmaceutical analysis.

Basic Information

Product Name	2'-Deoxy-5-Propyl-5'Uridylic Acid
CAS No.	64374-82-9
Molecular Formula	C12H18N2O8P
Molecular Weight	364.26 g/mol
Synonyms	5-Propyl-2'-deoxyuridine 5'-monophosphate; 5-Propyldeoxyuridylic Acid; dP-UMP; 2'-Deoxy-5-propyluridine 5'-monophosphate; 5-Propyl-dUMP; Deoxy-5-propyluridine monophosphate; 5-n-Propyl-2'-deoxyuridine 5'-phosphate; 64374-82-9
EINECS	Contact for details

Quality Control

Our 2'-Deoxy-5-Propyl-5'Uridylic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and tests for residual solvents and moisture content. We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with your research or development specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C or as indicated on the label. This material is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.