Description

N2-(2-Methylpropanoyl)-Guanosine is a chemically modified nucleoside derivative, specifically a guanosine analog. This compound is of significant interest in pharmaceutical research and development, particularly in the synthesis of novel antiviral and anticancer agents. It serves as a critical building block for researchers and manufacturers in the life sciences sector, enabling the creation of modified oligonucleotides and nucleotide-based therapeutics. Its precise chemical structure allows for targeted modifications to enhance drug stability, specificity, and efficacy.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of nucleoside-based antiviral drugs and anticancer prodrugs.
• Biochemical Research: Used as a substrate or inhibitor in enzymatic studies to understand nucleotide metabolism and related pathways.
• Proteomics & Molecular Biology: Employed in the development of labeled nucleotides for tracing, sequencing, and diagnostic applications.
• Antiviral Agent Development: Core scaffold for researching compounds active against viruses such as hepatitis and herpes.
• Oligonucleotide Synthesis: Building block for creating modified RNA or DNA strands with enhanced properties for therapeutic and diagnostic use.
• Chemical Biology Probes: Utilized to create probes for studying nucleic acid-protein interactions and cellular processes.

Basic Information

Product Name	N2-(2-Methylpropanoyl)-Guanosine
CAS No.	64350-24-9
Molecular Formula	C15H19N5O6
Molecular Weight	365.34 g/mol
Synonyms	N2-Isobutyryl-guanosine; 2'-Deoxy-N2-isobutyrylguanosine; Guanosine, N2-(2-methyl-1-oxopropyl)-; Isobutyryl Guanosine; N-Isobutyrylguanosine; 9-[(2R,3R,4S,5R)-3,4-Dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-2-(2-methylpropanoylamino)-1H-purin-6-one
EINECS	Contact for details

Quality Control

Our N2-(2-Methylpropanoyl)-Guanosine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements for pharmaceutical research and development. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment. We adhere to cGMP principles where applicable to support our clients' regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.