Description

1-(2,4-Difluorophenyl)Butane-1,3-Dione is a high-purity fluorinated diketone building block, essential for advanced organic synthesis. This compound matters for its role as a versatile precursor in the development of complex molecules, offering a reactive 1,3-diketone moiety and fluorinated aromatic system. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials industries for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the preparation of fluorinated heterocycles, such as pyrazoles and isoxazoles, which are core structures in many active pharmaceutical ingredients (APIs).
• Agrochemical Synthesis: Used in the research and production of novel fluorinated pesticides and herbicides, where the difluorophenyl group can enhance biological activity and metabolic stability.
• Ligand and Catalyst Development: Serves as a precursor for β-diketone ligands used in coordination chemistry and catalysis, particularly for lanthanide and transition metal complexes.
• Advanced Material Research: Employed in the synthesis of fluorinated organic compounds for electronic materials, liquid crystals, and polymers with specific optical or electronic properties.
• Chemical Research & Development: A valuable building block in medicinal chemistry and process chemistry for structure-activity relationship (SAR) studies and route scouting.

Basic Information

Product Name	1-(2,4-Difluorophenyl)Butane-1,3-Dione
CAS No.	64287-17-8
Molecular Formula	C10H8F2O2
Molecular Weight	198.17 g/mol
Synonyms	1,3-Butanedione, 1-(2,4-difluorophenyl)-; 2,4-Difluorophenyl-1,3-butanedione; 1-(2,4-Difluorophenyl)-1,3-butanedione; 2',4'-Difluorodibenzoylmethane; DFPD; 2,4-Difluorodibenzoylmethane; (2,4-Difluorophenyl)butane-1,3-dione
EINECS	Contact for details

Quality Control

Our 1-(2,4-Difluorophenyl)Butane-1,3-Dione is manufactured under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and IR spectroscopy, to ensure high chemical purity and identity. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specifications and test results. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring traceability, consistency, and reliability for your critical R&D and production needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be opaque or stored in dark conditions.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.