Description

4-(Trifluoromethoxy)Phenyl Isothiocyanate is a specialized organic building block featuring a phenyl ring substituted with both a trifluoromethoxy group and a highly reactive isothiocyanate functional group. This compound is valued for its role as a key intermediate in the synthesis of more complex molecules, particularly in advanced pharmaceutical and agrochemical research. It is primarily sought by R&D chemists and process development scientists in the life sciences and fine chemical industries for constructing novel compounds with potential biological activity.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in the development of new drug candidates.
• Agrochemical Research: Used in creating novel herbicides, fungicides, and insecticides where the trifluoromethoxy group can enhance metabolic stability and bioavailability.
• Ligand Synthesis: Serves as a precursor for isothiocyanate-derived ligands used in catalysis and material science applications.
• Bioconjugation Chemistry: The reactive isothiocyanate group allows for covalent attachment to amines, useful in labeling proteins, antibodies, or other biomolecules.
• Organic Synthesis: Employed in academic and industrial research for constructing heterocycles and other complex organic frameworks.
• Material Science Precursor: Can be utilized in the development of advanced polymers or functionalized surfaces.

Basic Information

Product Name	4-(Trifluoromethoxy)Phenyl Isothiocyanate
CAS No.	64285-95-6
Molecular Formula	C8H4F3NOS
Molecular Weight	219.18 g/mol
Synonyms	1-Isothiocyanato-4-(trifluoromethoxy)benzene; p-(Trifluoromethoxy)phenyl isothiocyanate; 4-(Trifluoromethoxyl)phenyl isothiocyanate; 4-Trifluoromethoxyphenyl isothiocyanate; 4-(Trifluoromethoxy)benzenisothiocyanate; [4-(Trifluoromethoxy)phenyl] isothiocyanate; 4-(Trifluoromethoxy)phenyl mustard oil
EINECS	Contact for details

Quality Control

Every batch of 4-(Trifluoromethoxy)Phenyl Isothiocyanate is produced and tested under strict quality management protocols to ensure consistency and purity for research and development applications. Our products undergo rigorous quality testing, including HPLC, NMR, and GC analysis, to ensure compliance with industry standards. Certificates of Analysis (COA) detailing purity and identity are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and light-sensitive; ensure containers are sealed under an inert atmosphere if specified and kept away from moisture and direct light to maintain stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.