Description

Cadralazine CAS NO 64241-34-5 is a potent, long-acting peripheral vasodilator belonging to the hydralazine chemical class. This compound is of significant interest in pharmaceutical research and development, particularly for its antihypertensive properties. It is primarily utilized by pharmaceutical companies, research institutions, and contract development and manufacturing organizations (CDMOs) engaged in cardiovascular drug discovery, formulation studies, and the synthesis of reference standards.

Application

• Pharmaceutical Active Ingredient (API): Serves as the core active component in the research and development of antihypertensive medications.
• Reference Standard: Used as a high-purity analytical standard in quality control (QC) and quality assurance (QA) laboratories for method development, validation, and impurity profiling.
• Biochemical Research: Employed in pharmacological studies to investigate mechanisms of vasodilation and hemodynamic effects.
• Formulation Development: A key material in pre-formulation and formulation studies for developing various dosage forms such as tablets or capsules.
• Process Chemistry: Used as an intermediate or final product in chemical process development, optimization, and scale-up activities.
• Regulatory Submissions: Supplied as a characterized material to support regulatory filings (e.g., IND, NDA, DMF) with agencies like the FDA and EMA.

Basic Information

Product Name	Cadralazine
CAS No.	64241-34-5
Molecular Formula	C10H16N6O
Molecular Weight	236.28 g/mol
Synonyms	Cadralazine; 2-[(E)-[6-(2-Cyclopropyl-1-oxido-1,2-dihydropyrazin-2-yl)pyridin-3-yl]methylidene]hydrazinecarboxamide; 2-[2-(6-(2-Cyclopropyl-1-oxo-1,2-dihydropyrazin-2-yl)pyridin-3-yl)vinyl]hydrazinecarboxamide; 2-[2-[6-(2-Cyclopropyl-1-oxidopyrazin-1-ium-2-yl)-3-pyridyl]vinyl]hydrazinecarboxamide; Cadralazinum; Brand names may include: Cadral; Pressural
EINECS	Contact for details

Quality Control

Our Cadralazine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including identification, purity assay, and impurity profiling using advanced techniques like HPLC and GC. We provide full traceability and Certificates of Analysis (COA) are supplied with every shipment, ensuring compliance with your research and development specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). The product is hygroscopic (moisture-sensitive); ensure the container is sealed after each use to minimize exposure to atmospheric humidity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Loss on Drying	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.