Description

Oxiconazole Nitrate is a synthetic broad-spectrum antifungal agent belonging to the imidazole class. Its primary value lies in its potent activity against a wide range of pathogenic fungi, including dermatophytes and yeasts, making it a critical active pharmaceutical ingredient (API). This compound is essential for manufacturers in the pharmaceutical industry developing topical antifungal formulations for the treatment of conditions such as athlete's foot, ringworm, and cutaneous candidiasis.

Application

• Pharmaceutical API: Primary use as the active ingredient in topical antifungal creams, ointments, and lotions.
• Dermatological Treatments: Formulated for treating tinea pedis (athlete's foot), tinea corporis (ringworm), and tinea cruris (jock itch).
• Antifungal Preparations: Used in products targeting cutaneous infections caused by Candida species and Malassezia furfur.
• Veterinary Medicine: Potential application in topical antifungal treatments for animals.
• Research & Development: Serves as a reference standard and key intermediate in pharmaceutical R&D for novel antifungal agents.

Basic Information

Product Name	Oxiconazole Nitrate
CAS No.	64211-46-7
Molecular Formula	C18H13Cl4N3O • HNO3
Molecular Weight	492.14 g/mol
Synonyms	Oxiconazole Nitrate; (Z)-1-(2,4-Dichlorophenyl)-2-(1H-imidazol-1-yl)ethanone O-[(2,4-dichlorophenyl)methyl]oxime nitrate; Ro 13-8996; Oxistat; Gyno-Myfungar; Myfungar
EINECS	Contact for details

Quality Control

Our Oxiconazole Nitrate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure it meets high-purity standards suitable for pharmaceutical use. We provide Certificates of Analysis (COA) detailing specifications for identity, purity, and impurities, referencing pharmacopeial methodologies. Compliance with cGMP and ICH Q7 guidelines is maintained throughout production.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which can affect stability and potency. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to almost white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Water Content (KF)	NMT 1.0%
Residue on Ignition	NMT 0.1%
Related Substances (HPLC)	Total impurities: NMT 2.0% Any individual impurity: NMT 0.5%
Heavy Metals	NMT 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.