Description

2-Fluoro-6-Pyridinecarbonyl Chloride is a versatile and highly reactive acyl chloride derivative, serving as a critical building block in advanced organic synthesis. Its core value lies in enabling the efficient introduction of the 2-fluoro-6-pyridinecarbonyl moiety, a key structural motif for modulating biological activity and material properties. This intermediate is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries developing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in kinase inhibitors and other targeted therapies.
• Agrochemical Synthesis: Used in creating advanced herbicides, fungicides, and insecticides with enhanced efficacy and selectivity.
• Ligand and Catalyst Development: Serves as a precursor for synthesizing specialized ligands used in catalysis and metal-organic frameworks (MOFs).
• Material Science: Employed in the production of functional polymers and advanced organic electronic materials.
• Chemical Research: A valuable reagent in academic and industrial R&D for exploring new heterocyclic compounds and reaction pathways.
• Peptide Mimetics: Facilitates the incorporation of fluorinated pyridine units into peptide backbones to improve metabolic stability.

Basic Information

Product Name	2-Fluoro-6-Pyridinecarbonyl Chloride
CAS No.	64197-03-1
Molecular Formula	C6H3ClFNO
Molecular Weight	159.55 g/mol
Synonyms	2-Fluoropyridine-6-carbonyl chloride; 6-(Chlorocarbonyl)-2-fluoropyridine; 2-Fluoro-6-pyridinylcarbonyl chloride; 2-Fluoropyridine-6-carboxylic acid chloride; 2-Fluoro-6-chlorocarbonylpyridine; 2-Fluoropyridine-6-carbonylchloride; 2-Fluoropyridine-6-carboxylic chloride; 2-Fluoropyridine-6-carboxychloride
EINECS	Contact for details

Quality Control

Our 2-Fluoro-6-Pyridinecarbonyl Chloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and consistency. We provide detailed Certificates of Analysis (COA) with every shipment, confirming compliance with customer specifications and relevant industry standards for fine chemical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at controlled room temperature (15-25°C). Due to its hygroscopic and reactive nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) to prevent moisture absorption and decomposition. Keep away from strong bases, oxidizing agents, and sources of ignition.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.