Description

4-Bromo-Picolinic Acid Chloride is a versatile and highly reactive halogenated heterocyclic building block. This compound is essential for the synthesis of complex molecules, particularly in the development of active pharmaceutical ingredients (APIs) and advanced agrochemicals. It is primarily sought after by research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for introducing the 4-bromopicolinoyl moiety into target structures.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly kinase inhibitors and other small molecule therapeutics.
• Agrochemical Synthesis: Used in the development of modern pesticides and herbicides, where the picolinic acid scaffold is a common pharmacophore.
• Ligand and Catalyst Preparation: Serves as a starting material for creating specialized ligands used in metal-catalyzed cross-coupling reactions.
• Material Science Research: Employed in the synthesis of organic electronic materials and functional polymers.
• Custom Synthesis and Contract Manufacturing: A critical building block for custom synthesis houses serving the life sciences sector.
• Bioconjugation and Probe Development: Useful for modifying biomolecules or creating fluorescent probes for biochemical research.

Basic Information

Product Name	4-Bromo-Picolinic Acid Chloride
CAS No.	64197-01-9
Molecular Formula	C6H3BrClNO
Molecular Weight	220.45 g/mol
Synonyms	4-Bromopicolinoyl Chloride; 4-Bromo-2-pyridinecarbonyl Chloride; 2-Pyridinecarbonyl Chloride, 4-Bromo-; 4-Bromopyridine-2-carboxylic Acid Chloride; 4-Bromo-2-pyridylcarbonyl Chloride; 4-Bromopicolinic Acid Chloride; 4-Bromopyridine-2-carbonyl Chloride; Picolinic Acid Chloride, 4-Bromo-
EINECS	Contact for details

Quality Control

Our 4-Bromo-Picolinic Acid Chloride is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay, identity, and impurity profiles. Our quality system is designed to meet the stringent requirements of cGMP and ISO standards for advanced chemical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) to prevent decomposition. Keep away from strong acids and organic solvents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Individual impurity ≤ 1.0%; Total impurities ≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.