Description

1-Piperidinecarbonyl Chloride, 2-Methyl- (9Ci) is a versatile and highly reactive acyl chloride derivative, primarily used as a key building block in advanced organic synthesis. Its core value lies in its ability to efficiently introduce the 2-methylpiperidinecarbonyl moiety, a crucial structural motif in medicinal chemistry. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly those developing active pharmaceutical ingredients (APIs) and novel bioactive molecules.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of complex drug candidates, especially those targeting the central nervous system (CNS).
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides, where the piperidine scaffold contributes to biological activity.
• Peptide Mimetics & PROTACs: Serves as a reagent for constructing peptide-like structures and proteolysis-targeting chimeras (PROTACs) in drug discovery.
• Material Science: Employed in the synthesis of specialty polymers and functional materials requiring specific amine-reactive handles.
• Chemical Research & Development: A valuable reagent for academic and industrial R&D labs exploring new synthetic methodologies and heterocyclic chemistry.

Basic Information

Product Name	1-Piperidinecarbonyl Chloride, 2-Methyl- (9Ci)
CAS No.	64196-60-7
Molecular Formula	C7H12ClNO
Molecular Weight	161.63 g/mol
Synonyms	2-Methylpiperidine-1-carbonyl chloride; 2-Methyl-1-piperidinecarbonyl chloride; 2-Methylpiperidine-1-carboxylic acid chloride; 1-Carboxy-2-methylpiperidine chloride; 2-Methylpiperidinocarbonyl chloride; 1-Piperidinecarbonyl chloride, 2-methyl-; (2-Methylpiperidin-1-yl)carbonyl chloride
EINECS	Contact for details

Quality Control

Our 1-Piperidinecarbonyl Chloride, 2-Methyl- (9Ci) is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. Certificates of Analysis (COA) with detailed specifications are provided for every shipment, supporting cGMP and ISO standards for traceability and reliability in your supply chain.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic and reactive nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) to prevent moisture absorption and decomposition. Keep away from strong acids, bases, and oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.