Description

3-Pyrazolidinecarbonyl Chloride, 5-Oxo- (9Ci) is a reactive heterocyclic acid chloride derivative, serving as a critical building block in advanced organic synthesis. Its value lies in enabling the efficient introduction of the 5-oxopyrazolidine-3-carbonyl moiety, a versatile scaffold for constructing complex molecules. This high-purity intermediate is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and metabolic diseases.
• Agrochemical Synthesis: Used in the development of advanced herbicides and fungicides, leveraging the pyrazolidinone core for biological activity.
• Peptidomimetic Research: Serves as a constrained scaffold in the design of peptide analogs to enhance stability and bioavailability.
• Material Science: Building block for specialty polymers and functional materials requiring specific heterocyclic architectures.
• Chemical Biology Probes: Utilized in the creation of activity-based probes and molecular tags for studying enzyme function.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for bespoke synthesis projects.

Basic Information

Product Name	3-Pyrazolidinecarbonyl Chloride, 5-Oxo- (9Ci)
CAS No.	64186-71-6
Molecular Formula	C4H5ClN2O2
Molecular Weight	148.55 g/mol
Synonyms	5-Oxo-3-pyrazolidinecarbonyl chloride; 5-Oxopyrazolidine-3-carbonyl chloride; 1,2-Diazolidine-3-carbonyl chloride, 5-oxo-; 3-Pyrazolidinecarbonyl chloride, 5-oxo-; 5-Oxo-1,2-diazolidine-3-carbonyl chloride; 5-Oxopyrazolidine-3-carboxylic acid chloride; 3-Carbamoylpyrazolidin-5-one chloride (uncommon); Contact for additional trade names.
EINECS	Contact for details

Quality Control

Our 3-Pyrazolidinecarbonyl Chloride, 5-Oxo- (9Ci) is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation by NMR and IR spectroscopy, to ensure it meets the high standards required for research and commercial synthesis. Certificates of Analysis (COA) detailing all specifications are provided with every shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic and reactive acid chloride nature, the container must be kept under an inert atmosphere (e.g., nitrogen or argon) after opening and protected from moisture. Keep away from strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.