Description

2-Pyrrolidinecarbonyl Chloride, 4,5-Dioxo- (9Ci) is a highly reactive acid chloride derivative of a pyrrolidine dione, serving as a critical building block in advanced organic synthesis. Its value lies in enabling the efficient introduction of the 4,5-dioxopyrrolidine-2-carbonyl moiety, a versatile scaffold for constructing complex molecules. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing novel active ingredients and fine chemicals. The CAS number for this product is 64154-86-5.

Application

This specialized reagent finds its primary utility in sophisticated chemical synthesis, offering a reactive handle for further functionalization.

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly those targeting neurological or metabolic disorders.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and plant growth regulators.
• Peptidomimetic Chemistry: Integral for constructing constrained peptide analogs and protease inhibitors due to its pyrrolidine dione core.
• Material Science Research: Serves as a monomer or cross-linking agent in the development of specialized polymers with unique properties.
• Chemical Biology Probes: Employed in the synthesis of activity-based probes for studying enzyme function and mechanism.

Basic Information

Product Name	2-Pyrrolidinecarbonyl Chloride, 4,5-Dioxo- (9Ci)
CAS No.	64154-86-5
Molecular Formula	C5H4ClNO3
Molecular Weight	161.54 g/mol
Synonyms	4,5-Dioxopyrrolidine-2-carbonyl chloride; 2-Carbamoyl-4,5-dioxopyrrolidine chloride; 4,5-Dioxo-2-pyrrolidinecarbonyl chloride; NSC 403914; Pyrrolidine-2-carbonyl chloride, 4,5-dioxo-; 1H-Pyrrole-2-carbonyl chloride, 4,5-dihydro-4,5-dioxo-
EINECS	Contact for details

Quality Control

Our production of 2-Pyrrolidinecarbonyl Chloride, 4,5-Dioxo- (9Ci) adheres to stringent quality protocols to ensure batch-to-batch consistency and reliability for your critical syntheses. Each lot undergoes comprehensive analytical characterization, including HPLC for purity and NMR for structural confirmation. Certificates of Analysis (COA) detailing all specifications are provided with every shipment, supporting your quality management and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic and moisture-sensitive nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent decomposition. Keep away from heat, sparks, open flames, and incompatible materials such as strong bases, alcohols, and water.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.