Description

Dimethyl 1-(4-Nitrobenzyloxycarbonyl)-1-Propene-2-Yl=Phosphate is a specialized organophosphorus compound featuring a nitrobenzyloxycarbonyl (Nvoc) protecting group. This chemical is a critical intermediate in advanced organic synthesis, particularly valued for its role in the controlled release of active moieties under photochemical or mild reductive conditions. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of prodrugs, peptide synthesis, and novel materials science applications.

Application

• Photolabile Protecting Group Reagent: Key intermediate in the synthesis of compounds requiring light-sensitive deprotection strategies.
• Pharmaceutical Intermediate: Used in the research and development of prodrugs and targeted drug delivery systems.
• Peptide Chemistry: Serves as a phosphorylating agent or a protected intermediate in the synthesis of complex peptides and phosphopeptides.
• Chemical Biology Research: Employed in the study of enzyme kinetics, signal transduction pathways, and the development of biochemical probes.
• Agrochemical Synthesis: Potential intermediate for developing novel active ingredients with specific release mechanisms.
• Materials Science Precursor: Used in the creation of functionalized polymers and advanced materials with responsive properties.

Basic Information

Product Name	Dimethyl 1-(4-Nitrobenzyloxycarbonyl)-1-Propene-2-Yl=Phosphate
CAS No.	64050-55-1
Molecular Formula	C13H16NO8P
Molecular Weight	345.24 g/mol
Synonyms	Dimethyl (1-(((4-Nitrobenzyl)oxy)carbonyl)-1-propen-2-yl) Phosphate; 1-Propen-2-ylphosphonic Acid, 1-(((4-Nitrobenzyl)oxy)carbonyl)-, Dimethyl Ester; (1-(((4-Nitrobenzyl)oxy)carbonyl)-1-propen-2-yl)phosphonic Acid Dimethyl Ester; Nvoc-Protected Propenyl Phosphate Ester; 4-Nitrobenzyl (1-Dimethoxyphosphoryl)vinyl Carbonate
EINECS	Contact for details

Quality Control

Our Dimethyl 1-(4-Nitrobenzyloxycarbonyl)-1-Propene-2-Yl=Phosphate is manufactured under strict quality control protocols to ensure high purity and batch-to-batch consistency, suitable for sensitive research and development applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to cGMP principles where applicable to support our clients in pharmaceutical and advanced material sectors.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and decomposition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.