Description

6-Methyl-3-Pyridinecarbonyl Azide is a versatile heterocyclic building block and reagent, primarily valued for its role as a precursor in click chemistry and heterocyclic synthesis. Its significance lies in its ability to participate in Curtius rearrangement and cycloaddition reactions, enabling the efficient construction of complex molecular architectures. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors, particularly for developing novel active ingredients and functional polymers.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, including kinase inhibitors and other bioactive heterocycles.
• Agrochemical Synthesis: Used in the development of advanced pesticides and herbicides with improved efficacy and selectivity.
• Click Chemistry Reagent: Serves as an azide component in copper-catalyzed azide-alkyne cycloaddition (CuAAC) reactions for bioconjugation and polymer functionalization.
• Material Science: Building block for creating functional polymers, dendrimers, and smart materials with specific thermal or optical properties.
• Curtius Rearrangment Substrate: Used to generate isocyanates in situ, which are subsequently trapped to form carbamates, ureas, and amines.
• Chemical Biology Probes: Utilized in the design and synthesis of activity-based probes for studying enzyme function and protein labeling.

Basic Information

Product Name	6-Methyl-3-Pyridinecarbonyl Azide
CAS No.	64038-04-6
Molecular Formula	C7H6N4O
Molecular Weight	162.15 g/mol
Synonyms	3-Azidocarbonyl-6-methylpyridine; 6-Methylnicotinoyl Azide; 6-Methylpyridine-3-carbonyl Azide; 3-(Azidocarbonyl)-6-methylpyridine; 6-Methyl-3-pyridylcarbonyl Azide; 6-Methylnicotinic Acid Azide; 6-Methyl-3-pyridinecarboxylic Acid Azide
EINECS	Contact for details

Quality Control

Our 6-Methyl-3-Pyridinecarbonyl Azide is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and FTIR, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic and light-sensitive nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) when not in use to prevent moisture absorption and decomposition. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.