Description

2-Azidoadenosine 5'-Monophosphate is a chemically modified nucleotide analog, specifically an azido-functionalized derivative of adenosine monophosphate. This compound is a critical building block and photoaffinity labeling reagent in biochemical research, enabling the study of nucleotide-binding sites and enzyme mechanisms. It is primarily utilized by researchers and manufacturers in the fields of pharmaceutical development, proteomics, and molecular biology for creating probes and investigating adenosine-related pathways.

Application

• Photoaffinity Labeling: Acts as a crucial cross-linking agent to identify and study nucleotide-binding proteins and enzyme active sites.
• Bioconjugation & Probe Synthesis: Serves as a key intermediate for synthesizing fluorescent, affinity, or radioactive probes via click chemistry, leveraging the reactive azido group.
• Enzymology Research: Used as a substrate analog to investigate the kinetics and inhibition of kinases, phosphorylases, and other ATP/AMP-utilizing enzymes.
• Structural Biology Studies: Employed in X-ray crystallography and NMR to elucidate the structure and function of nucleotide-binding domains.
• Drug Discovery: Functions as a precursor in the development of potential antiviral or anticancer agents that target purinergic signaling pathways.
• Diagnostic Assay Development: Incorporated into the design of assays for detecting specific enzymatic activities or biomolecular interactions.

Basic Information

Product Name	2-Azidoadenosine 5'-Monophosphate
CAS No.	64020-54-8
Molecular Formula	C10H12N8O7P
Molecular Weight	378.22 g/mol
Synonyms	2-Azido-AMP; 2-Azidoadenosine monophosphate; 2-N3-AMP; 2-Azido-5'-adenylic acid; 9-β-D-Ribofuranosyl-2-azidoadenine 5'-monophosphate; Adenosine-2-azido-5'-monophosphate; 2-Azido-5'-O-phosphonoadenosine
EINECS	Contact for details

Quality Control

Our 2-Azidoadenosine 5'-Monophosphate is produced under stringent quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for research and development. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting purity, assay, and impurity profiles.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive) and light-sensitive. For long-term storage, consider desiccation and storage under inert atmosphere to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/UV)	Conforms
Purity (HPLC)	≥ 95%
Assay	≥ 90% (on anhydrous basis)
Water Content (KF)	≤ 5.0%
Solubility	Soluble in water, DMSO

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.