Description

(S)-4-(2-Azidoethyl)-2,2,4-Trimethyl-1,3-Dioxolane is a chiral, azide-functionalized dioxolane derivative, serving as a critical building block in advanced organic synthesis. Its value lies in its dual functionality, combining a protected diol moiety with a reactive azide group suitable for click chemistry applications, particularly the copper-catalyzed azide-alkyne cycloaddition (CuAAC). This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries who require high-purity chiral intermediates for the development of novel active ingredients and complex molecules.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of complex drug candidates, including antiviral and central nervous system (CNS) active compounds.
• Click Chemistry Reagent: The azido group enables efficient, high-yield conjugation reactions (CuAAC) for bioconjugation, polymer modification, and materials science.
• Agrochemical Synthesis: Used in the research and development of novel, optically active pesticides and herbicides.
• Ligand and Catalyst Development: Acts as a precursor for chiral ligands and organocatalysts used in asymmetric synthesis.
• Polymer Science: Serves as a functional monomer for creating specialty polymers with tailored properties via post-polymerization modification.
• Proteomics and Chemical Biology: Utilized for labeling biomolecules and developing activity-based probes for target identification.

Basic Information

Product Name	(S)-4-(2-Azidoethyl)-2,2,4-Trimethyl-1,3-Dioxolane
CAS No.	64018-45-7
Molecular Formula	C9H17N3O2
Molecular Weight	199.25 g/mol
Synonyms	(S)-2,2,4-Trimethyl-4-(2-azidoethyl)-1,3-dioxolane; (S)-4-(2-Azidoethyl)-2,2,4-trimethyl-1,3-dioxolane; (S)-1,2-Isopropylidene glycerol 3-azidopropyl ether; (S)-3-Azidopropyl 2,2-dimethyl-1,3-dioxolane-4-methanol; Azido-functionalized (S)-Solketal derivative
EINECS	Contact for details

Quality Control

Our (S)-4-(2-Azidoethyl)-2,2,4-Trimethyl-1,3-Dioxolane is produced under strict quality management systems to ensure batch-to-batch consistency and high purity. We provide comprehensive analytical data, including chiral purity (enantiomeric excess) and assay by validated methods such as HPLC and GC. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available for every batch upon request, supporting your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, open flames, and incompatible materials. Due to the presence of the azide functional group, avoid shock, friction, and contact with heavy metals.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC/GC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.