Description

5,14-Dihydroxy-19-Oxo-3β-[(Phenylacetyl)Oxy]-5β-Card-20(22)-Enolide is a high-purity, complex steroidal lactone compound of significant interest in advanced pharmaceutical research and development. This specialized intermediate is valued for its precise molecular structure, which serves as a critical building block in the synthesis of novel bioactive molecules. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical and biotechnology sectors for applications in cardiac drug discovery and steroid chemistry.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the research and development of novel cardiotonic agents and other steroidal pharmaceuticals.
• Cardiac Drug Discovery: Used as a core scaffold or advanced intermediate in medicinal chemistry programs targeting heart failure and related cardiovascular conditions.
• Steroid Chemistry Research: Serves as a model compound or starting material for studying structure-activity relationships (SAR) in modified steroid frameworks.
• Reference Standard: Employed as an analytical standard in quality control laboratories for the identification and quantification of related compounds.
• Biochemical Research: Utilized in academic and industrial research to investigate interactions with biological targets such as Na+/K+-ATPase.
• Process Chemistry: Acts as an intermediate in the multi-step synthesis of complex natural product analogs and potential drug candidates.

Basic Information

Product Name	5,14-Dihydroxy-19-Oxo-3β-[(Phenylacetyl)Oxy]-5β-Card-20(22)-Enolide
CAS No.	63979-71-5
Molecular Formula	C31H38O7
Molecular Weight	522.63 g/mol
Synonyms	19-Oxobufalin 3-phenylacetate; 3β-[(Phenylacetyl)oxy]-5,14-dihydroxy-19-oxo-5β-card-20(22)-enolide; Bufalin-3-phenylacetate-19-one; 5β,14β-Dihydroxy-19-oxo-3β-(phenylacetoxy)card-20(22)-enolide; 19-Oxo-3β-phenylacetoxybufalin; A common cardiac glycoside derivative intermediate
EINECS	Contact for details

Quality Control

Our 5,14-Dihydroxy-19-Oxo-3β-[(Phenylacetyl)Oxy]-5β-Card-20(22)-Enolide is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, IR and NMR for structural confirmation, and residual solvent analysis. We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with your research or development specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). The product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.