Description

2,8-Dimethyladenosine is a modified nucleoside analog of adenosine, featuring methyl groups at the 2 and 8 positions of the purine ring. This structural modification is of significant interest in biochemical research and pharmaceutical development, particularly for studying enzyme interactions and as a potential precursor in nucleoside-based therapeutics. It is primarily utilized by research institutions, pharmaceutical R&D departments, and fine chemical manufacturers engaged in the synthesis of novel bioactive compounds.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the research and synthesis of novel antiviral or anticancer nucleoside analogs.
• Biochemical Research: Used as a substrate or inhibitor in enzymatic studies, particularly those involving adenosine deaminase, kinases, and other purine-metabolizing enzymes.
• Reference Standard: Employed as a high-purity analytical standard in quality control laboratories for method development and compound identification via HPLC or LC-MS.
• Life Science Reagents: Incorporated into specialized cell culture media or diagnostic assay kits for probing specific metabolic pathways.
• Academic Research: Utilized in universities and research institutes for fundamental studies on nucleic acid chemistry, epigenetics, and signal transduction.

Basic Information

Product Name	2,8-Dimethyladenosine
CAS No.	63954-66-5
Molecular Formula	C₁₂H₁₇N₅O₄
Molecular Weight	295.30 g/mol
Synonyms	2,8-Dimethyl-9-β-D-ribofuranosyladenine; 2,8-Dimethyladenosine; 9-((2R,3R,4S,5R)-3,4-Dihydroxy-5-(hydroxymethyl)oxolan-2-yl)-2,8-dimethylpurin-6-amine; 2,8-Dimethyl-9-β-D-ribofuranosyl-9H-purin-6-amine; N6-Amino-2,8-dimethyl-9-β-D-ribofuranosylpurine
EINECS	Contact for details

Quality Control

Our 2,8-Dimethyladenosine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity assessment and spectroscopic methods (NMR, IR) for structural confirmation, to ensure it meets the high standards required for research and development applications. Certificates of Analysis (COA) with detailed batch-specific results are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container should be kept in a desiccated environment to prevent moisture absorption, which may affect stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.