Description

2-(1-Cbz-4-Piperidyl)Acetyl Chloride is a high-purity, reactive chemical intermediate essential for advanced organic synthesis. This compound is valued for its role as a key building block in the construction of complex pharmacologically active molecules. It is primarily sought after by research institutions and manufacturers in the pharmaceutical and fine chemical industries for developing new therapeutic agents.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in medicinal chemistry research and development.
• Peptide Mimetics Synthesis: Used in the preparation of peptidomimetics and other bioactive compounds that mimic the function of natural peptides.
• Chemical Biology Probes: Employed in the creation of specialized molecular probes for studying biological pathways and target identification.
• Library Compound Generation: Serves as a versatile scaffold for generating diverse compound libraries in high-throughput screening for drug discovery.
• Custom Synthesis: Utilized by contract research and manufacturing organizations (CROs/CMOs) for bespoke synthesis projects requiring a protected piperidine derivative.

Basic Information

Product Name	2-(1-Cbz-4-Piperidyl)Acetyl Chloride
CAS No.	63845-29-4
Molecular Formula	C15H18ClNO3
Molecular Weight	295.76 g/mol
Synonyms	1-[(Benzyloxy)carbonyl]-4-(chloroacetyl)piperidine; 4-(Chloroacetyl)-1-[(phenylmethoxy)carbonyl]piperidine; 1-Cbz-4-(Chloroacetyl)piperidine; N-Cbz-4-Piperidylacetyl Chloride; 1-(Carbobenzyloxy)-4-(chloroacetyl)piperidine; 4-(Chloroacetyl)-1-[(benzyloxy)carbonyl]piperidine; 2-(1-[(Benzyloxy)carbonyl]piperidin-4-yl)acetyl chloride
EINECS	Contact for details

Quality Control

Our 2-(1-Cbz-4-Piperidyl)Acetyl Chloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specifications and test results to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic and moisture-sensitive nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from strong acids and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.