Description

5α-Cholestane-3α,7α,12α,25,26,27-Hexaol is a high-purity, polyhydroxylated sterol derivative of significant interest in biochemical research and pharmaceutical development. This compound serves as a critical reference standard and synthetic intermediate for studying bile acid biosynthesis and metabolic pathways. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel therapeutics and diagnostic agents for metabolic and liver-related disorders.

Application

• Pharmaceutical Reference Standard: Used as a certified reference material (CRM) for the quantitative analysis and quality control of related sterols and bile acid precursors in drug development.
• Biochemical Research: Serves as a key intermediate or substrate in enzymatic studies related to sterol metabolism, particularly in the investigation of hydroxylation pathways.
• Metabolic Pathway Analysis: Employed in metabolic studies to trace and understand the biosynthesis and catabolism of bile acids and other steroidal compounds.
• Academic & Industrial R&D: A vital tool for synthetic chemists and biologists in universities and corporate R&D labs for creating novel steroid-based molecules.
• Diagnostic Reagent Development: Potential use in the formulation of calibration standards for clinical diagnostic kits targeting specific metabolic markers.

Basic Information

Product Name	5α-Cholestane-3α,7α,12α,25,26,27-Hexaol
CAS No.	63780-55-2
Molecular Formula	C27H48O6
Molecular Weight	468.67 g/mol
Synonyms	5α-Cholestane-3α,7α,12α,25,26,27-hexol; 3α,7α,12α,25,26,27-Hexahydroxy-5α-cholestane; 25,26,27-Trihydroxycholestane-3α,7α,12α-triol; 5α-Cholestanehexol; Cholestane-3α,7α,12α,25,26,27-hexaol
EINECS	Contact for details

Quality Control

Every batch of 5α-Cholestane-3α,7α,12α,25,26,27-Hexaol is manufactured under a strict quality management system and undergoes comprehensive analytical testing to ensure identity, purity, and consistency. Our products are suitable for use as analytical reference standards in regulated environments. A detailed Certificate of Analysis (COA) providing batch-specific results for purity, identity, and related substances is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container should be kept in a desiccated environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.